Diphenoxylate-atropine

Drug Details

Lomotil, a combination of diphenoxylate and atropine, is an antidiarrheal medication designed to treat diarrhea in individuals aged 13 and older. Diphenoxylate, an opioid-like substance, functions primarily by slowing intestinal movements, which reduces the frequency and number of bowel movements. Atropine, an anticholinergic, complements this effect by helping to dry up body fluids and further slow gut movement. Typically, the medication is administered four times daily until symptoms are controlled, then the dosage is reduced. It is available in both brand-name and generic forms and is classified as a controlled substance, meaning there may be specific dispensing requirements. Common side effects include sleepiness, dizziness, and nausea. It is crucial not to use this medication to treat diarrhea caused by certain infections, such as those associated with C. difficile following antibiotic treatment. It is also not recommended for children under 6 years due to the risk of severe side effects, including breathing issues. Always consult your healthcare provider for personalized medical advice before starting or adjusting any medication regimen.