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When taking this medication, it's important to be aware of potential side effects, although they are rare. The most common ones include darkening of the stools or tongue. These effects are harmless and will resolve once you stop taking the medication. Most individuals on this medication experience no serious side effects. However, persistent vomiting or diarrhea could lead to dehydration. Be alert for symptoms like unusual decreased urination, dry mouth, intense thirst, a fast heartbeat, or dizziness, and contact a healthcare professional if these occur.

More serious side effects, although uncommon, require immediate attention. These include ringing in the ears or hearing loss. Additionally, this medication may rarely cause severe bleeding from the stomach or intestines. If you experience persistent stomach pain, vomit resembling coffee grounds, or black, tarry, or bloody stools, discontinue use and seek medical advice promptly.

A severe allergic reaction is very rare, but if you experience symptoms such as a rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing, seek emergency medical attention immediately. While this list covers significant side effects, it's not exhaustive. If you notice any other unusual effects, contact a healthcare professional for guidance.

Certain medications may interact with this drug. These include valproic acid, carbonic anhydrase inhibitors like acetazolamide, corticosteroids such as prednisone, dichlorphenamide, and methotrexate. Taking this medication alongside drugs that also increase bleeding risk can heighten the chance of bleeding. Examples of such drugs include anti-platelet medications like clopidogrel and anticoagulants such as dabigatran, enoxaparin, and warfarin.

It's important to review all your prescription and over-the-counter medications, as many contain NSAIDs—like aspirin, ibuprofen, or naproxen—that are similar to this drug and could increase the likelihood of side effects. However, if your doctor has advised you to take low-dose aspirin (81-162 milligrams daily) to prevent heart attack or stroke, continue taking it unless instructed otherwise by your healthcare provider. Consult your doctor or pharmacist for more guidance.

Additionally, this medication may affect certain medical or laboratory tests, such as intestinal x-rays using contrast dye, potentially leading to inaccurate results. Ensure that all healthcare professionals involved in your care are informed that you are taking this medication.