
Zidovudine Coupons & Discount Card - Compare Prices Near You
generic Retrovir
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100MG, Zidovudine (30 Capsules)
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CVS
$73.23
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Walgreens
$4.22
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Rite Aid
$17.77
COUPON PRICEZidovudine savings card
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CVS
$73.23
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ID
PCN
GRP
019876
LH99E64494
CHIPPO
LHX
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Zidovudine dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
100MG | 30 Capsules | $4.22 | $0.14 |
Zidovudine Warnings
Zidovudine, also known as Retrovir, is a medication used in the treatment of HIV, but it comes with important safety considerations that must be understood. Below are the potential risks, precautions, and actions you should take if you experience any concerning symptoms while on this medication:
Blood and Bone Marrow Issues: Zidovudine can cause serious blood problems, such as anemia (a decrease in red blood cells) and neutropenia (a decrease in white blood cells), which are more common in individuals with advanced HIV. These conditions may necessitate blood transfusions or discontinuation of the medication. Regular blood tests will be conducted to monitor your blood counts. Seek immediate medical attention if you notice signs of anemia like unusual fatigue, breathing difficulties, weakness, bluish nails or lips, pale skin, or a rapid heartbeat. Low white blood cell counts can increase your risk of severe infections, so contact your healthcare provider if you develop a persistent cough, fever, chills, breathing issues, or a sore throat.
Muscle Problems: Prolonged use of zidovudine may lead to muscle pain, weakness, or myopathy. If you experience unexplained fatigue, muscle pain, or weakness throughout your body, inform your healthcare provider promptly.
Liver Problems: Zidovudine can rarely cause severe liver issues and a metabolic disorder known as lactic acidosis, particularly in women and obese patients. Symptoms include persistent nausea, stomach pain, dark urine, jaundice (yellowing of the eyes or skin), rapid breathing, drowsiness, and muscle aches. Discontinue use and seek emergency medical care if these symptoms occur.
Immune Reconstitution Syndrome: As your immune system recovers with zidovudine treatment, it may begin to fight existing infections, potentially causing significant inflammation. Your healthcare provider may check for infections before starting treatment. Contact your provider if you experience a fever, breathing difficulties, or sudden health changes after initiating zidovudine.
Fat Redistribution: Some individuals on HIV antiretrovirals like zidovudine may experience changes in body fat distribution, such as increased fat in the abdomen and back and decreased fat in the face, arms, legs, and buttocks. Although the exact cause is unknown, switching medications may help, though changes may not be fully reversible.
In case of an overdose, seek immediate medical attention. Always adhere to your healthcare provider's instructions and keep all medical appointments to ensure the safe and effective use of zidovudine.
Zidovudine Side Effects
Common side effects:
- Headaches
- Fatigue
- Nausea
- Loss of appetite
- Vomiting
- Weakness or lack of energy
- Constipation
Serious side effects:
- Unexplained weight loss
- Severe fatigue
- Persistent muscle aches or weakness
- Severe headaches
- Joint pain
- Numbness and tingling in extremities
- Signs of infection (fever, swollen lymph nodes, trouble breathing)
- Changes in skin or fingernail color
- Easy bruising or bleeding
- Mood changes (depression or anxiety)
- Seizures
- Allergic reaction (rash, severe dizziness, trouble breathing)
- Unusual changes in body fat distribution
Zidovudine Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Orlistat
- Probenecid
- Ribavirin
- Stavudine
- Ganciclovir
- Dapsone
- Trimethoprim
- Doxorubicin
- Vincristine
- Cabotegravir
- Clarithromycin
- Pexidartinib
- Pyrimethamine
- Vinblastine
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Methadone
- Rifampin
- Phenytoin
- Valproic Acid
- Acetaminophen
- Fluconazole
- Interferon Beta-1a
- Nelfinavir
- Rifabutin
- Rifapentine
- Tipranavir
What is the medication zidovudine used for?
Zidovudine is used to treat HIV infection. It is an antiretroviral medication that helps to decrease the amount of HIV in the body, thereby improving the immune system function and reducing the risk of developing HIV-related complications. It is also used to prevent mother-to-child transmission of HIV during childbirth.
Why is zidovudine no longer used?
Zidovudine is still used, but its use has decreased due to the development of newer antiretroviral drugs that are more effective and have fewer side effects. Zidovudine was one of the first drugs used to treat HIV, but newer medications offer better viral suppression and improved safety profiles. However, it may still be used in certain situations, such as in combination therapies or for preventing mother-to-child transmission of HIV during childbirth.
Is zidovudine AZT or ZDV?
Zidovudine is commonly referred to as both AZT and ZDV. AZT stands for azidothymidine, which is an older name for the drug, while ZDV is the abbreviation for zidovudine. Both terms are used interchangeably.
What does zidovudine do in babies?
Zidovudine is used in babies to reduce the risk of mother-to-child transmission of HIV. It is typically administered to newborns whose mothers are HIV-positive, starting shortly after birth and continuing for a period of time to help prevent the virus from establishing an infection in the infant.
What replaced AZT?
AZT, also known as zidovudine, was one of the first antiretroviral drugs used to treat HIV. Over time, it has been largely replaced by newer antiretroviral medications that are more effective and have fewer side effects. These newer drugs are often used in combination therapies, known as Highly Active Antiretroviral Therapy (HAART) or Antiretroviral Therapy (ART), which include medications such as tenofovir, emtricitabine, and efavirenz, among others. These combinations are tailored to provide a more comprehensive approach to managing HIV infection.