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This medication carries significant safety warnings that should be thoroughly reviewed. If you have concerns about using this drug, please consult your healthcare provider. Here are the key safety considerations and potential risks associated with the use of amphetamines:

• Misuse, Addiction, and Dependency: Amphetamines pose a risk of misuse and can lead to addiction. Misusing amphetamines can result in severe side effects such as elevated heart rate and blood pressure, depression, aggressive behavior, and even suicidal thoughts. Long-term use can lead to physical dependence, and abrupt cessation may result in withdrawal symptoms like irritability and sleep disturbances. Increased risk exists for those with a history of substance or alcohol use disorder, those taking higher doses than prescribed, and those using the drug long-term.

• Cardiovascular Risks: There have been instances of sudden death, stroke, and heart attack in individuals taking amphetamines, even at prescribed doses. The medication may increase blood pressure and heart rate. Inform your healthcare provider of any pre-existing heart conditions before commencing treatment. Monitor for symptoms such as unexplained fainting, chest pain during physical activity, or irregular heartbeat.

• Behavioral and Mental Health Effects: Amphetamines can exacerbate or induce mental health issues, including hallucinations, aggressive behavior, and mania, even in those without prior mood disorders. Immediate consultation with a healthcare provider is advised if these symptoms emerge.

• Growth Impacts in Children: Amphetamines may negatively impact growth in children, affecting both weight and height. Regular monitoring of growth by a healthcare provider is essential. Treatment may be adjusted if significant weight loss or growth suppression is observed.

• Seizure Risk: Although rare, amphetamines may increase the likelihood of seizures, particularly in individuals with a seizure history. Seek immediate medical attention if seizures occur.

• Raynaud's Phenomenon: Amphetamines can cause decreased blood flow to the extremities, leading to color changes, coldness, numbness, or pain in the fingers and toes. Although typically mild, severe cases may require dose adjustment or discontinuation.

• Serotonin Syndrome: This potentially life-threatening condition can occur due to elevated serotonin levels, especially when combined with other serotonin-influencing drugs such as certain antidepressants and migraine medications. Symptoms include rapid heartbeat, sweating, muscle stiffness, high fever, and confusion. Immediate medical attention is necessary if these symptoms present.

• Vision Problems: Some individuals may experience blurred vision or other visual disturbances. Notify your healthcare provider if any changes in vision occur.

Contraindications: Amphetamines should not be used by individuals with certain heart conditions, moderate-to-severe high blood pressure, an overactive thyroid, feelings of agitation, a history of drug misuse, or those currently using or having recently used monoamine oxidase inhibitors (MAOIs). Always consult with your healthcare provider before starting this medication if these conditions apply.

In case of overdose, seek emergency medical assistance immediately. Adhering to prescribed dosages and consulting healthcare professionals with any concerns can help mitigate these risks.

When taking this medication, you may experience some mild side effects, such as nausea, stomach upset, diarrhea, dry mouth, headache, nervousness, dizziness, trouble sleeping, loss of appetite, weight loss, irritability, or restlessness. While these effects are generally not serious, inform your healthcare provider if they persist or worsen.

It's important to be aware of more serious side effects that require prompt medical attention. These include changes in mood or behavior, such as agitation, aggression, mood swings, depression, thoughts of suicide, hallucinations, or abnormal thoughts. Additionally, watch for signs of blood flow problems, such as coldness, numbness, pain, or skin color changes in fingers or toes. Uncontrolled muscle movements, vision changes, and swelling of the ankles or feet are also concerns.

Seek immediate medical help if you experience very serious side effects like fainting, severe headache, fast or irregular heartbeat, seizures, symptoms of a heart attack, or stroke. There is also a risk of serotonin syndrome, characterized by fast heartbeat, hallucinations, loss of coordination, severe dizziness, and unusual agitation. This condition is rare but serious and requires urgent care.

Allergic reactions to this medication are rare but can be severe. Symptoms include rash, itching or swelling of the face, tongue, or throat, severe dizziness, and trouble breathing. If you notice these symptoms, seek emergency medical attention. While this is not an exhaustive list of side effects, it highlights the most significant ones. If you experience any other unusual symptoms, contact your healthcare provider for guidance.

Using this medication alongside MAO inhibitors can lead to a severe and potentially fatal interaction. It is crucial to avoid MAO inhibitors such as isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine while on this medication. Most MAO inhibitors should also be discontinued at least two weeks before starting this treatment. Consult your healthcare provider to determine the appropriate timing for starting or stopping this medication.

Some products may increase heart rate or blood pressure. Inform your pharmacist about all the products you are using, particularly cough-and-cold remedies, diet aids, or NSAIDs like ibuprofen and naproxen, to ensure safe usage.

The chance of developing serotonin syndrome or toxicity rises if you are concurrently using drugs that elevate serotonin levels. This includes substances like MDMA ("ecstasy"), St. John's wort, and certain antidepressants, such as SSRIs (e.g., fluoxetine, paroxetine) and SNRIs (e.g., duloxetine, venlafaxine). The risk is heightened when initiating or increasing the dose of these drugs.

Amphetamine is quite similar to dextroamphetamine and lisdexamfetamine, so avoid using medications that contain either of these while taking amphetamine.

This medication might affect certain medical and laboratory tests, including blood and urine steroid levels and brain scans for Parkinson's disease, potentially causing inaccurate results. Ensure all your healthcare providers and lab technicians are aware that you are using this medication.