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It is important to use methylphenidate correctly to avoid serious heart and blood pressure complications, which can be life-threatening. Here are some important safety points to consider:

• Methylphenidate has the potential for habit formation. Individuals with mental health conditions or a history of substance misuse, including alcohol or drug addiction, should exercise caution when using this medication.
• Inform your healthcare provider if you or your family have a history of substance use disorders before starting this medication.
• Do not alter the dosage or frequency, nor extend the duration of use beyond what has been prescribed by your doctor. Misuse can lead to reduced effectiveness, dependence, or unusual thoughts and behaviors.
• If you have been on methylphenidate for an extended period or at higher doses, your doctor may continue to monitor your health after discontinuation to ensure your safety.

Please follow these guidelines to use methylphenidate safely and discuss any concerns with your healthcare provider.

You may experience some mild side effects such as nervousness, difficulty sleeping, loss of appetite, weight loss, dizziness, nausea, vomiting, headaches, or mild irritation/redness at the application site. These are generally not a cause for concern, but if they persist or worsen, consult your healthcare provider.

There is a possibility that this medication might increase your blood pressure. Regular monitoring is advisable, and any significant rise should be reported to your healthcare provider.

Serious side effects, though uncommon, require immediate attention. These include circulatory issues in fingers or toes (e.g., coldness, numbness), unusual wounds, a fast or irregular heartbeat, mood or behavioral changes, uncontrolled muscle movements, sudden vocal outbursts, or vision changes. Also, sores or ulcers on fingers or toes that heal slowly should be promptly addressed.

Seek urgent medical help for severe reactions such as fainting, seizures, heart attack symptoms (like chest pain or shortness of breath), strokes (such as sudden weakness or speech difficulties), or any severe allergic reactions characterized by rash, swelling, or breathing difficulties.

In rare instances, males, including young boys, might experience a painful or prolonged erection lasting over four hours. This requires immediate medical attention to prevent lasting damage.

Additionally, this medication may cause the skin under the patch to lighten, potentially permanently. Notify your healthcare provider if you notice any changes in skin color.

This summary does not cover all possible side effects. If you observe any other unusual effects, it is important to reach out to your healthcare provider for guidance.

Using MAO inhibitors together with this medication can lead to a significant and potentially life-threatening interaction. It is important to avoid taking MAO inhibitors such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, and Tranylcypromine while on this treatment. Additionally, most MAO inhibitors should not be used for at least two weeks before starting this medication. Consult your doctor for guidance on when to begin or discontinue this medication.

Methylphenidate is closely related to Dexmethylphenidate, and you should not use dexmethylphenidate-containing products while taking methylphenidate.

This medication may affect the results of certain medical or laboratory tests, such as a brain scan for Parkinson's disease, leading to inaccurate outcomes. Ensure that all healthcare providers and laboratory staff are aware that you are taking this medication.