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This document outlines important safety information and warnings related to the use of galantamine. It is crucial to understand these risks and take necessary precautions. If you have any concerns or experience any unusual symptoms, contact your healthcare provider promptly.

• Serious Skin Reactions: Though infrequent, galantamine may cause severe skin reactions. If you notice a rash, inform your healthcare provider immediately, as discontinuation of the medication may be necessary.

• Slowed Heartbeat and Fainting: Galantamine can lead to a reduced heart rate, which may result in fainting. Report any instances of falls or feelings of lightheadedness to your healthcare provider.

• Stomach Ulcers and Bleeding: This medication can increase stomach acid production, raising the risk of ulcers and bleeding. The use of nonsteroidal anti-inflammatory drugs (NSAIDs), often present in over-the-counter cold and pain medications, can further elevate this risk. It is advisable to avoid combining these medications with galantamine. Contact your healthcare provider if you experience worsening stomach upset, heartburn, or indigestion, especially if you have a history of stomach ulcers or bleeding.

• Seizures: There is a potential risk of seizures associated with galantamine use. If you suspect you have had a seizure, seek medical advice immediately.

No specific contraindications are noted for galantamine, but it is always recommended to discuss your medical history with your healthcare provider to ensure safe use of this medication.

Common side effects:

• nausea
• vomiting
• dizziness
• diarrhea
• low appetite
• headache
• weight loss

Less common but important to monitor:

• upset stomach
• stomach pain
• sleepiness
• tiredness
• weakness
• falls
• shakiness
• depression

Serious side effects:

• slow heartbeat
• difficulty urinating
• seizures
• black or bloody stools
• vomit resembling coffee grounds
• severe stomach or abdominal pain
• fast or irregular heartbeat
• severe dizziness
• fainting
• chest pain
• rash
• itching
• swelling of the face, tongue, or throat
• trouble breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Bepridil
• Cisapride
• Dronedarone
• Mesoridazine
• Pimozide
• Piperaquine
• Saquinavir
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone
• Benzgalantamine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Amiodarone
• Aripiprazole
• Buprenorphine
• Chloroquine
• Clarithromycin
• Fluoxetine
• Hydroxychloroquine
• Methadone
• Quetiapine

Interactions with low risk that usually do not require a change in therapy:

• Amitriptyline
• Fluvoxamine
• Ketoconazole
• Oxybutynin
• Paroxetine
• Quinidine
• Tolterodine