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Lomustine is a medication that can significantly impact bone marrow function, potentially resulting in a dangerously low level of blood cells, including red cells, white cells, and platelets. This may lead to conditions such as anemia, increased susceptibility to infections, and an elevated risk of bruising or bleeding. These adverse effects typically manifest 4 to 6 weeks post-administration and can persist for 1 to 2 weeks.

Consider the following precautions and actions:

• Immediately inform your healthcare provider if you experience symptoms like unusual fatigue, pale complexion, persistent sore throat, fever, chills, or easy bruising and bleeding.
• Your doctor will conduct weekly blood tests for at least six weeks following each dose to monitor your condition. Your treatment plan, including dosage and future administration, will be adjusted based on these test results.
• Due to the potential for severe side effects, do not take Lomustine more frequently than once every six weeks. Adhere strictly to your healthcare provider's guidance.

By following these instructions, you can help manage the risks associated with Lomustine treatment effectively.

Patients taking this medication might experience nausea, vomiting, loss of appetite, diarrhea, or mouth and lip sores. Nausea and vomiting typically last less than 24 hours, while loss of appetite may persist for several days. These symptoms can be severe, but eating small meals, avoiding food before treatment, or reducing activity might help alleviate them. Temporary hair loss is possible, but hair generally regrows after treatment concludes.

Although many people taking this medication do not encounter serious side effects, it's important to be aware of them. Notify your healthcare provider right away if you experience confusion, swelling in the lower legs or feet, or vision changes. Severe side effects requiring immediate medical attention include persistent stomach or abdominal pain, black stools, vomit resembling coffee grounds, yellowing of the eyes or skin, dark urine, or signs of kidney issues like changes in urine amount or pink urine.

A serious lung condition known as pulmonary fibrosis has been reported, which can develop months or years after starting the medication. Symptoms such as cough, chest pain, and difficulty or painful breathing should be addressed immediately by a medical professional. Though rare, severe allergic reactions can occur. Seek urgent medical help if you notice rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing. Always contact your healthcare provider if you notice any other unusual effects.