Valganciclovir

Drug Details

Valganciclovir is an oral antiviral medication used to prevent and treat infections caused by the cytomegalovirus (CMV). It is particularly important for individuals who have received organ transplants to prevent CMV, and for people with advanced HIV (AIDS) to treat CMV retinitis—a serious eye infection that can lead to blindness. Once inside the body, valganciclovir is converted to its active form, ganciclovir. This active compound stops the CMV virus from replicating by inhibiting an enzyme called DNA polymerase, thus slowing the virus's growth and preventing the spread of infection. For prevention, the medication is generally taken once daily, but for treating an active CMV infection, it may be taken twice daily initially. Valganciclovir is available in tablet form and as an oral solution, with generic versions offering a cost-effective option. While valganciclovir helps manage CMV infections, it is not a cure. Regular eye examinations are crucial for those with CMV retinitis to monitor and manage the condition effectively. Common side effects may include diarrhea, fever, and fatigue. Always consult with a healthcare provider for personalized medical advice before starting this medication.