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Valganciclovir

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generic Valcyte

Valganciclovir is an anti-viral drug. It is changed in the body to the active form of the drug called ganciclovir. It is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received organ transplants. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness. Valganciclovir works by slowing the growth of the CMV virus. It helps prevent the spread of infection to other areas of the body. Valganciclovir is also used to treat CMV retinitis in people with advanced HIV disease (AIDS). This medication helps control CMV retinitis and decrease the risk of blindness. Valganciclovir is not a cure for CMV disease. Some people may have worsening CMV retinitis even with treatment. It is important to have your eyes checked regularly by your doctor.
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WarningsValganciclovir Side EffectsInteractionsFAQs

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450MG, Valganciclovir (30 Tablets)

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Warnings

Valganciclovir turns into the drug ganciclovir inside your body. Ganciclovir can decrease bone marrow function. This serious, possibly life-threatening side effect may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, and cause bleeding problems. Your doctor will check the results of your blood tests and adjust your treatment to reduce your risk for these side effects. Get medical help right away if you develop signs of anemia (such as unusual tiredness, fast breathing, pale skin, fast heartbeat), signs of infection (such as sore throat that doesn't go away, fever, chills, cough), and signs of bleeding (such as easy bruising/bleeding, nose bleeds, bleeding gums, bloody/black/tarry stools, vomit that looks like coffee grounds). Ganciclovir may reduce fertility in men and women. It may also harm an unborn baby. Talk to your doctor for more details. Ganciclovir has caused tumors in lab animals. Although there is no information in humans, valganciclovir should be considered cancer-causing (carcinogenic). See also How to Use and Precautions sections.

Valganciclovir Side Effects

Diarrhea, upset stomach, dizziness, drowsiness, unsteadiness, or shaking (tremors) may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), signs of kidney problems (such as change in the amount of urine), seizures. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: imipenem/cilastatin, maribavir. You may be taking other drugs that decrease bone marrow function and lower your number of blood cells (such as cancer chemotherapy, trimethoprim/sulfamethoxazole, zidovudine) or other drugs that may cause kidney problems (such as cyclosporine). Your doctor or pharmacist will monitor you closely and adjust your medications to decrease your risk of serious side effects. Valganciclovir is very similar to ganciclovir. Do not use medications containing ganciclovir while using valganciclovir.
Valganciclovir FAQs
What is the drug valganciclovir used for?

Valganciclovir is used to treat cytomegalovirus (CMV) infections, particularly in patients with weakened immune systems, such as those with HIV/AIDS or organ transplant recipients. It is also used to prevent CMV disease in high-risk organ transplant patients.

Valganciclovir is considered a hazardous drug because it has the potential to cause significant adverse effects, including teratogenicity (risk of causing birth defects), carcinogenicity (potential to cause cancer), and reproductive toxicity. It can also cause myelosuppression, leading to decreased blood cell counts, which can increase the risk of infections and bleeding. Due to these risks, special handling precautions are necessary to protect healthcare workers and patients.

Another name for Valtrex is Valacyclovir.

Valganciclovir is not classified as a carcinogen. However, it has been shown to be mutagenic in some laboratory tests, and long-term use may carry a potential risk of cancer. It is important for patients to discuss the risks and benefits of valganciclovir with their healthcare provider.

Valcyte (valganciclovir) is not a chemotherapy drug. It is an antiviral medication used to treat cytomegalovirus (CMV) infections, particularly in people with weakened immune systems, such as organ transplant recipients.

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