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Griseofulvin microsize is used to treat fungal infections of the skin, hair, and nails. It works by inhibiting the growth of fungi, helping to clear up the infection.

Griseofulvin has not been universally discontinued, but its use has declined in some regions due to the availability of newer antifungal medications that are more effective, have a broader spectrum of activity, and often have more convenient dosing regimens. Additionally, some manufacturers may have stopped producing it due to decreased demand. However, it may still be available and used in certain cases where it is deemed appropriate by a healthcare provider.

The most common side effect of griseofulvin is headache. Other potential side effects can include nausea, vomiting, diarrhea, and fatigue, but headache is reported most frequently.

A substitute for griseofulvin, which is used to treat fungal infections, could be terbinafine or itraconazole. The choice of substitute depends on the specific type of fungal infection and the patient's medical history. It is important for the patient to consult with a healthcare provider to determine the most appropriate alternative.

Griseofulvin can potentially cause liver toxicity, although it is relatively uncommon. Patients taking griseofulvin should have their liver function monitored, especially if they have pre-existing liver conditions or are taking other medications that affect the liver. It is important to report any symptoms of liver dysfunction, such as jaundice, dark urine, or abdominal pain, to a healthcare provider.