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Estradiol

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This medication is a hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment. Certain estrogen products may also be used by men and women to treat cancers (certain types of prostate cancer, breast cancer that has spread to other parts of the body) and by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).
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WarningsEstradiol Side EffectsInteractionsFAQs

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0.5MG, Estradiol (90 Tablets)

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$20.61

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$9.81

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$10.90

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Warnings

Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding. In postmenopausal women, estrogens, taken with or without a progestin, increase the risk of cancer of the breast/ovaries, stroke, dementia, and serious blood clots. When used along with a progestin, estrogens also increase the risk of heart disease (such as heart attacks). The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. This medication should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of this medication with your doctor regularly (for example, every 3 to 6 months) to see if you still need to use it. If you will be taking this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor.

Estradiol Side Effects

Stomach upset, nausea/vomiting, bloating, breast tenderness, headache, or weight changes may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Tell your doctor promptly if you see the tablet in your stool. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: nausea/vomiting that doesn't stop, mental/mood changes (such as depression, memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach/abdominal pain, yellowing eyes/skin, dark urine, swelling hands/ankles/feet, increased thirst/urination. This medication may rarely cause serious (sometimes fatal) problems from blood clots (such as heart attack, stroke, blood clots in the lungs or legs). Get medical help right away if you have: chest/jaw/left arm pain, unusual sweating, sudden/severe headaches, weakness on one side of the body, confusion, trouble speaking, sudden vision changes, pain/swelling/warmth in the groin/calf, shortness of breath/rapid breathing, sudden dizziness/fainting. A very serious allergic reaction to this product is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), fezolinetant, fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid. This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Estradiol FAQs
What does estradiol do to the body?

Estradiol is a form of estrogen, a hormone that plays a crucial role in the development and regulation of the female reproductive system and secondary sexual characteristics. It helps regulate the menstrual cycle, supports the growth of the uterine lining, and is involved in the development of breasts. Estradiol also has effects on other body systems, including maintaining bone density, influencing mood and cognitive function, and affecting skin health. In males, estradiol is present in smaller amounts and is important for modulating libido, erectile function, and spermatogenesis.

Estradiol can potentially lead to weight changes in some individuals, but it does not universally cause weight gain. The effect of estradiol on weight can vary depending on individual factors such as metabolism, lifestyle, and overall health. If there are concerns about weight changes while taking estradiol, it is advisable to discuss them with a healthcare provider.

Estradiol is a form of estrogen, which is a group of hormones. Estrogen includes several types, with estradiol being the most potent and prevalent form in women of reproductive age.

Doctors prescribe estradiol primarily for hormone replacement therapy in individuals experiencing symptoms of menopause, such as hot flashes, vaginal dryness, and osteoporosis prevention. It is also used in hormone therapy for transgender women and in certain cases of estrogen deficiency due to hypogonadism or ovarian failure. Additionally, estradiol may be prescribed for the treatment of certain types of breast cancer and prostate cancer.

Estradiol is a specific form of estrogen, which is a group of hormones responsible for the development and regulation of the female reproductive system and secondary sexual characteristics. Estrogen is a broader term that includes several types of hormones, with estradiol being the most potent and prevalent form in premenopausal women. Other forms of estrogen include estrone and estriol.

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