Eplerenone Coupons & Discount Card – Guaranteed Prices from $16.60
generic Inspra
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25MG, Eplerenone (30 Tablets)
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CVS
$23.70
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$16.60
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$18.16
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$26.94
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$31.85
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$16.60
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GRP
019876
LHECD86974
CHIPPO
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Eplerenone dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 25MG | 30 Tablets | $16.6 | $0.55 |
| 50MG | 30 Tablets | $21.1 | $0.7 |
Eplerenone Warnings
The following information outlines crucial safety warnings and potential risks associated with the use of this medication. Please read carefully and consult your healthcare provider with any concerns.
High Potassium Levels (Hyperkalemia): Eplerenone (Inspra) may lead to elevated potassium levels in the blood, which can disrupt heart rhythm and, in severe cases, result in cardiac arrest. Individuals with kidney problems, diabetes, or those using certain other medications (such as ACE inhibitors, ARBs, or NSAIDs) are at an increased risk. If you experience sudden numbness, tingling, nausea, or muscle weakness, contact your healthcare provider immediately, as a dosage adjustment might be necessary.
Contraindications: This medication should not be used in the following situations, as it can lead to serious health complications:
- Presence of very high potassium levels.
- Severe kidney impairment.
- Concurrent use of particular drugs such as ketoconazole, ritonavir (Norvir), or clarithromycin.
For individuals with high blood pressure, additional contraindications include:
- Type 2 diabetes with elevated urine protein levels (microalbuminuria).
- Moderate to severe kidney issues.
- Concurrent use of potassium supplements or potassium-sparing diuretics like spironolactone (Aldactone), amiloride (Midamor), or triamterene (Dyrenium).
If any of these conditions apply to you, it is essential to speak with your healthcare provider before starting this medication to ensure your safety.
Eplerenone Side Effects
Common side effects:
- Headaches
- Dizziness
- Diarrhea
- Vomiting
- Digestive issues
- Nervous system problems
- Urinary tract discomfort
- Shortness of breath
- Skin reactions
- Mental health changes
- Cough
Less common but important to monitor:
- Chest pain
- Heart attack
- Gynecomastia
- Abnormal vaginal bleeding
Serious side effects:
- High potassium levels
- Muscle weakness
- Slow or irregular heartbeat
- Nausea
- Numbness or tingling
- Very serious allergic reaction
- Rash
- Itching or swelling
- Severe dizziness
- Trouble breathing
Eplerenone Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Amiloride
- Clarithromycin
- Cobicistat
- Itraconazole
- Ketoconazole
- Spironolactone
- Triamterene
- Lithium
- Nelfinavir
- Ritonavir
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Adagrasib
- Nefazodone
- St. John's wort
- Telithromycin
- Licorice
Interactions with low risk that usually do not require a change in therapy:
What is eplerenone prescribed for?
Eplerenone is prescribed primarily for the treatment of high blood pressure (hypertension) and heart failure, particularly after a heart attack. It helps to lower blood pressure and reduce the risk of heart failure-related complications.
What drugs should not be taken with eplerenone?
Eplerenone should not be taken with certain medications due to potential interactions. These include:1. Potassium supplements or potassium-sparing diuretics, as they can increase the risk of hyperkalemia (high potassium levels).2. Strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, and clarithromycin, which can increase eplerenone levels in the blood.3. ACE inhibitors or angiotensin II receptor blockers (ARBs) may also increase the risk of hyperkalemia when used together with eplerenone.It is important for individuals to consult with their healthcare provider before starting or stopping any medications while taking eplerenone.
What is a good replacement for spironolactone?
A suitable replacement for spironolactone depends on the condition being treated. For hypertension or heart failure, alternatives might include other diuretics like eplerenone, which is also a potassium-sparing diuretic. For acne or hormonal issues, options could include oral contraceptives or anti-androgens like flutamide. It's important for the patient to consult with their healthcare provider to determine the most appropriate alternative based on their specific medical needs and history.
What is a major adverse effect of eplerenone?
A major adverse effect of eplerenone is hyperkalemia, which is an elevated level of potassium in the blood. This condition can be serious and requires monitoring, especially in patients with renal impairment or those taking other medications that increase potassium levels.
Can you take lisinopril with eplerenone?
It is generally not recommended to take lisinopril with eplerenone without close medical supervision. Both medications can increase potassium levels in the blood, which may lead to hyperkalemia, a condition that can be dangerous. A healthcare provider should be consulted to evaluate the potential risks and benefits, and to monitor potassium levels if these medications are used together.