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Ketotifen fumarate is used to relieve symptoms of allergic conjunctivitis, such as itching, redness, and swelling of the eyes. It is an antihistamine that helps to block the release of histamine, a substance in the body that causes allergic symptoms.

Ketotifen is considered a relatively mild antihistamine. It is often used for its mast cell stabilizing properties in addition to its antihistamine effects. It is commonly used to manage allergic conditions such as allergic conjunctivitis and asthma.

Ketotifen and Benadryl are not the same. Ketotifen is an antihistamine often used to treat allergic conditions and is available in some countries as an eye drop for allergic conjunctivitis. Benadryl, on the other hand, contains diphenhydramine, which is also an antihistamine but is commonly used for allergy relief, as a sleep aid, and for motion sickness. While both are antihistamines, they contain different active ingredients and may be used for different purposes.

Ketotifen can cause weight gain as a side effect due to its antihistamine properties, which may increase appetite. Additionally, it can have a sedative effect, potentially leading to decreased physical activity. These factors combined can contribute to weight gain in some individuals.

It is generally not recommended to take ketotifen with Benadryl without consulting a healthcare provider. Both medications are antihistamines and taking them together may increase the risk of side effects such as drowsiness, dry mouth, and dizziness. It is important to seek advice from a healthcare professional to ensure safe and appropriate use of these medications.