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When considering the use of Benazepril (Lotensin), it is crucial to be aware of the safety concerns and potential risks associated with this medication. Below is a summary of the vital warnings and precautions you should be familiar with:

• Pregnancy Risks: This medication can severely harm an unborn baby, especially if taken during pregnancy. It may lead to birth defects, issues with organ development, or even fetal death, particularly during the second or third trimester. It is essential to avoid pregnancy while on this drug. If you are pregnant, planning to become pregnant, or suspect you might be pregnant, consult your doctor immediately and discontinue use.

• Angioedema: Benazepril may cause angioedema, characterized by swelling of the face, lips, tongue, or throat, which can occur at any time. This condition might also affect your stomach, causing nausea or vomiting. Those who are Black, older adults, or female are at a higher risk. Seek urgent medical care if you experience difficulty breathing or swelling. Special caution is advised if taking mTOR inhibitors.

• Kidney Issues: While generally beneficial for kidney function, Benazepril can occasionally exacerbate kidney problems, particularly in individuals with renal artery stenosis or severe heart failure. Regular kidney function tests may be required. Notify your healthcare provider if you notice decreased urination.

• Elevated Potassium Levels: The medication can increase potassium levels, posing a risk to heart health. Individuals with diabetes, pre-existing kidney issues, or those on other potassium-raising drugs have an elevated risk. Symptoms of high potassium, such as nausea, muscle weakness, or irregular heartbeat, require immediate medical attention.

• Low Blood Pressure: Benazepril lowers blood pressure, which may cause dizziness or lightheadedness, especially after dose changes. Risks are heightened for those with heart issues or dehydration. If you feel dizzy, support yourself when changing positions and contact your doctor.

• Liver Concerns: Rare cases of blocked bile ducts, leading to liver problems or failure, have been reported with ACE inhibitors like Benazepril. Routine liver function tests may be necessary. Report symptoms such as fatigue, abdominal pain, or jaundice promptly.

Contraindications:

• A history of angioedema.
• Concurrent use of Benazepril with neprilysin inhibitors (such as sacubitril) or aliskiren (Tekturna) in diabetic patients.

Always discuss your medical history and current medications with your healthcare provider to ensure safe use of Benazepril. Contact your healthcare professional immediately if you experience any adverse effects or have concerns regarding this medication.

When taking this medication, you may experience some common side effects such as dizziness, lightheadedness, drowsiness, headache, or a dry cough. These effects are typically mild and often diminish as your body adjusts. To minimize dizziness and lightheadedness, try standing up slowly after sitting or lying down. Should any of these effects persist or worsen, it's advisable to consult your healthcare provider.

More serious side effects, although rare, require immediate medical attention. These include symptoms of high blood potassium levels like muscle weakness or an irregular heartbeat, and severe kidney issues, which can manifest as a change in urination patterns. Additionally, this medication may rarely cause serious liver problems. Be alert for signs such as persistent nausea or vomiting, loss of appetite, abdominal pain, yellowing of the skin or eyes, or dark urine.

A very serious allergic reaction is also rare but warrants urgent medical care if you notice symptoms such as rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. Always communicate with your healthcare provider if you experience any unexpected side effects or if they cause concern.

Benazepril, also known as Lotensin, can interact with various medications, which may affect your treatment or increase the risk of side effects. It's crucial to inform your doctor and pharmacist about all the medications and supplements you take, whether they are prescribed, over-the-counter, or herbal.

Certain drugs should not be used with Benazepril. These include aliskiren and sacubitril. In some cases, Benazepril may be used with other medications, but careful monitoring and dosage adjustments might be necessary. These medications include everolimus, sirolimus, lithium, and drugs that can raise potassium levels in the blood, such as angiotensin receptor blockers (ARBs) like losartan and valsartan, and birth control pills containing drospirenone.

Other medications, such as NSAIDs like ibuprofen and naproxen, can increase the risk of side effects when taken with Benazepril. Additionally, if you are undergoing desensitization therapy for bee or wasp sting allergies, inform your healthcare provider, as a serious reaction can occur when combined with Benazepril.

Always communicate openly with your healthcare team to ensure safe and effective use of Benazepril, considering all potential interactions.