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When using this medication, it's important to be aware of potential risks and necessary precautions. This medication may compromise your immune system, potentially increasing your likelihood of developing severe infections or exacerbating existing ones. Users of oral ruxolitinib have experienced serious and sometimes fatal infections, such as fungal infections, tuberculosis, and herpes zoster.

• Immediately inform your healthcare provider if you notice any signs of infection, such as a persistent sore throat, ongoing cough, fever, chills, excessive sweating, or painful skin rashes/blisters.
• There have also been reports of cancer (including skin cancer) and blood clots among individuals using ruxolitinib cream.
• A similar medication, when taken orally, has been linked to severe, potentially fatal side effects, including heart issues, blood clots, and cancer such as lymphoma.

Before starting treatment with ruxolitinib, disclose any history of heart disease, stroke, cancer, or risk factors for heart disease to your doctor or pharmacist. These risk factors include high blood pressure, diabetes, previous blood clots, high cholesterol, and smoking history. Individuals aged 50 and older may be more susceptible to heart problems or blood clots. Discuss the potential risks and benefits of this treatment with your healthcare provider.

Seek immediate medical attention if you experience any of the following symptoms: shortness of breath or rapid breathing, chest, jaw, or left arm pain, unusual sweating, sudden dizziness or fainting, pain, swelling, or warmth in the groin or calf, sudden and severe headaches, difficulty speaking, confusion, abrupt changes in vision, or weakness on one side of the body.

While taking this medication, you might experience some side effects, although many people do not encounter serious issues. Common side effects could include mild tiredness or slight bruising. These are generally manageable and should not cause alarm. However, it's essential to be aware of more serious side effects. If you notice signs of anemia, such as unusual tiredness or pale skin, or experience easy bleeding or bruising, it's important to seek medical advice promptly.

Although it's rare, severe allergic reactions can occur. If you experience symptoms such as a rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek immediate medical attention. These symptoms indicate a serious condition that requires urgent care. Remember, this list does not cover all possible side effects. If you notice any other unusual symptoms, please consult your healthcare provider for guidance. Always prioritize your health and well-being by staying informed about the potential effects of your medication.