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This document outlines essential safety warnings and contraindications for the use of oxybutynin. It's important to carefully consider these points and discuss any concerns with your healthcare provider.

• Angioedema (Swelling of Face, Lips, Tongue): Oxybutynin may cause swelling in areas such as the face, lips, tongue, throat, or other organs, which could lead to breathing difficulties. If you experience persistent swelling in the head or neck, contact your healthcare provider immediately.

• Hallucinations, Drowsiness, and Confusion: Taking oxybutynin can result in confusion, drowsiness, or hallucinations, particularly within the first few months of treatment or after a dose increase. These effects are more likely with higher doses, concurrent use of anticholinesterase drugs for dementia, or in patients with nervous system conditions like Parkinson's disease. Avoid driving or engaging in alertness-requiring activities until you understand how oxybutynin affects you. Consult your provider if these symptoms occur, as dosage adjustments or alternative treatments may be needed.

• Exacerbation of Other Conditions: Oxybutynin may worsen symptoms of certain medical conditions, including myasthenia gravis, urinary difficulties, or specific gastrointestinal issues such as ulcerative colitis or acid reflux. Use with caution if you have a history of these conditions.

• Heat Exhaustion Risk: This medication can impair the body's ability to sweat, increasing the risk of overheating in hot weather or during exercise. To prevent heat exhaustion or heat stroke, stay hydrated and avoid exposure to high temperatures when possible.

Contraindications:

• Urinary Difficulties: Oxybutynin should not be used if you have trouble urinating.

• Gastrointestinal Motility Issues: Avoid this medication if you have movement problems in your stomach or intestines.

• Uncontrolled Narrow Angle Glaucoma: Do not use oxybutynin if you have this condition, as it may pose serious health risks.

Always consult your healthcare provider before starting oxybutynin, particularly if any of the above warnings or contraindications apply to you.

Common side effects:

• Dry mouth
• Dizziness
• Constipation
• Drowsiness
• Nausea
• Blurred vision

Less common but important to monitor:

• Headache
• Diarrhea
• Upset stomach
• Unusual tastes in the mouth
• Dry or flushed skin
• Weakness
• Feelings of nervousness

Serious side effects:

• Severe allergic reactions (rash, swelling of face, tongue, throat)
• Angioedema
• Difficulty urinating
• Mental changes (confusion)
• Fast or pounding heartbeat
• Signs of kidney infection (painful urination, lower back pain)
• Seizures
• Significant vision problems
• Stomach or intestinal blockage symptoms

Interactions with high risk of serious adverse effects and should be avoided:

• Potassium

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Bupropion
• Clozapine
• Donepezil
• Glucagon
• Glycopyrrolate
• Methacholine
• Quetiapine
• Revefenacin
• Scopolamine
• Secretin Human
• Tiotropium

Interactions with low risk that usually do not require a change in therapy:

• Galantamine
• Ketoconazole
• Rivastigmine
• Opioid pain relievers (e.g., codeine, hydrocodone)
• Alcohol
• Marijuana
• Sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem)
• Muscle relaxants
• Antihistamines