Prucalopride Succinate Coupons & Savings Card – Discount Prices from $45.00

Prucalopride succinate is a medication prescribed for chronic idiopathic constipation in adults. While it can be effective, certain individuals should avoid its use due to specific health conditions. These include those with a known allergy to prucalopride, individuals undergoing dialysis for end-stage kidney disease, and those with serious gastrointestinal issues such as intestinal perforation, obstruction, or severe inflammatory diseases like Crohn's disease and ulcerative colitis.

Additionally, prucalopride is not recommended for use in children under 18 years of age, as its safety and effectiveness in this group have not been established. For individuals with severe kidney impairment, a reduced dosage is advised, and the medication should be avoided in those requiring dialysis.

It's important to note that prucalopride may cause mood changes, including depression and suicidal thoughts, particularly during the initial weeks of treatment. Patients should be closely monitored for any new or worsening mental health symptoms, and the medication should be discontinued if such symptoms occur.

Before starting prucalopride, discuss your full medical history with your healthcare provider to ensure it's a safe option for you.

Common side effects:

• Nausea
• Abdominal pain
• Diarrhea
• Headache
• Dizziness
• Tiredness

Less common but important to monitor:

• Fast or irregular heartbeat
• Severe abdominal pain
• Bloody diarrhea
• Rectal bleeding
• Mental or mood changes (e.g., depression or suicidal thoughts)

Serious side effects:

• Allergic reaction (rash, itching, swelling of the face, tongue, or throat, severe dizziness, difficulty breathing)

When taking prucalopride succinate, it's important to be aware of potential interactions with other medications:

• Anticholinergic Agents: Medications like atropine or Dicyclomine may reduce the effectiveness of prucalopride. These drugs can slow down gut movements, counteracting prucalopride's action. If you're using such medications, your doctor may need to monitor your response to prucalopride more closely.

• P-glycoprotein (P-gp) Inhibitors: Drugs such as Ketoconazole, Verapamil, Cyclosporine, and quinidine can increase prucalopride levels in your body. While this increase is generally small and not usually a concern, it's important to inform your healthcare provider about all the medications you're taking.

• Oral Contraceptives: Prucalopride does not significantly affect the absorption of oral contraceptives. However, if you experience severe diarrhea while on prucalopride, the effectiveness of your birth control pills might be reduced. In such cases, using an additional contraceptive method is advisable.

• Fosfomycin: Prucalopride may decrease the absorption of fosfomycin, an antibiotic. If you're prescribed both, your doctor may adjust the timing of doses or monitor the effectiveness of the antibiotic treatment.

Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you're taking to ensure safe and effective use of prucalopride.