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This medication requires careful attention to safety information due to its associated risks. Please read the following details thoroughly and discuss any concerns with your healthcare provider.

• Dehydration and Electrolyte Imbalance: Kristalose (lactulose) may lead to dehydration, impacting your body's mineral balance. Essential electrolytes such as sodium, potassium, and calcium could be affected. Regular monitoring by a healthcare professional is advisable, particularly for individuals over 65 or those on long-term Kristalose (lactulose) therapy. If you experience symptoms like extreme thirst, fatigue, or confusion, contact your healthcare provider immediately, as these may indicate dehydration and electrolyte disturbances. The risk is heightened for those over 65, with prolonged use, or on other medications that disrupt electrolyte levels.

• Blood Sugar Elevations: Kristalose (lactulose) contains sugars like galactose and lactose, which could potentially influence blood sugar levels. Although current studies suggest no significant blood sugar spikes, individuals with diabetes should regularly monitor their blood glucose while on this medication.

• Colonoscopy Preparation: If you are scheduled for a colonoscopy or rectal examination, inform your healthcare team about your use of Kristalose (lactulose). Alternative bowel preparation methods may be recommended.

• Contraindications: Do not use Kristalose (lactulose) if you require a low-galactose diet, as it may pose significant health risks. Always consult your healthcare provider if this applies to you.

By adhering to these precautions and consulting with your healthcare provider, you can use Kristalose (lactulose) safely and effectively.

When taking this medication, you might experience some common side effects like gas, bloating, burping, stomach rumbling, and mild cramps. These symptoms are usually not serious and tend to resolve on their own. However, if they persist or become bothersome, it's advisable to consult a healthcare professional. Additionally, nausea and diarrhea have also been reported by some users.

For more serious concerns, be vigilant for symptoms such as severe or persistent stomach pain, vomiting, muscle cramps or weakness, an irregular heartbeat, mood changes, seizures, bloody stools, or rectal bleeding. These require immediate medical attention. Moreover, although rare, a serious allergic reaction could occur. Seek urgent medical assistance if you experience symptoms like rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing.

Remember, this summary does not cover all possible side effects. If you notice any other unusual symptoms, contacting a healthcare provider is recommended.

Kristalose (lactulose) can interact with various medications and supplements. It is important to inform your healthcare provider about all the medications, including over-the-counter drugs, vitamins, and herbal supplements, that you are currently taking.

Interactions with certain medications are not recommended. Your doctor might suggest discontinuing one of these medications or adjusting the dosages. Medications in this category include: Amantadine, Atropine, Belladonna, Belladonna Alkaloids, Benztropine, Bepridil, Biperiden, Burosumab-twza, Cisapride, Clidinium, Darifenacin, Dicyclomine, Dronedarone, Eplerenone, Fesoterodine, Glycopyrrolate, Hyoscyamine, Mesoridazine, Methscopolamine, Oxybutynin, Pimozide, Piperaquine, Procyclidine, Saquinavir, Scopolamine, [Solifenacin](https://savehealth.com/solifenacin), Sparfloxacin, Terfenadine, Thioridazine, Tolterodine, Trihexyphenidyl, Trospium, and Ziprasidone.

In some cases, Kristalose might be used with other medications, although it is not usually recommended. If both are necessary, your doctor may adjust the dose or frequency of one or both medications. These include: Acalabrutinib, Alacepril, Alfuzosin, Amiloride, Amiodarone, Amisulpride, Amitriptyline, Amoxapine, Amphetamine, Amygdalin, Anagrelide, Apomorphine, Aripiprazole, Aripiprazole Lauroxil, Arsenic Trioxide, Asenapine, Astemizole, Azathioprine, Azithromycin, Baloxavir Marboxil, Bedaquiline, Benazepril, Benzphetamine, Bictegravir, Bisacodyl, Bupivacaine, Buprenorphine, Buserelin, Cabotegravir, Canrenoate, Captopril, Ceritinib, Chloroquine, Chlorpromazine, Cilazapril, Ciprofloxacin, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clozapine, Crizotinib, Cyclobenzaprine, Cyclosporine, Dabrafenib, Dasatinib, Deferoxamine, Degarelix, Delamanid, Delapril, Desipramine, Deslorelin, Deutetrabenazine, Dextroamphetamine, Digoxin, Dimercaprol, Disopyramide, Dofetilide, Dolasetron, Dolutegravir, Domperidone, Donepezil, Droperidol, Efavirenz, Eltrombopag, Elvitegravir, Encorafenib, Entrectinib, Erdafitinib, Erythromycin, Escitalopram, Fingolimod, Flecainide, Fluconazole, Fluoxetine, Formoterol, Foscarnet, Fosinopril, Fostemsavir, Gatifloxacin, Gefitinib, Gemifloxacin, Glasdegib, Gonadorelin, Goserelin, Granisetron, Halofantrine, Haloperidol, Histrelin, Hyaluronidase, Hydroxychloroquine, Hydroxyzine, Ibutilide, Iloperidone, Imidapril, Imipramine, Indomethacin, Inotuzumab Ozogamicin, Ivabradine, Ivosidenib, Ketoconazole, Lamivudine, Lapatinib, Ledipasvir, Lefamulin, Lenvatinib, Levofloxacin, Levomethadyl, Licorice, Lisdexamfetamine, Lisinopril, Lofexidine, Lopinavir, Lumefantrine, Macimorelin, Mefenamic Acid, Mefloquine, Memantine, Mercaptopurine, Methadone, Methamphetamine, Metronidazole, Mifepristone, Mirtazapine, Moexipril, Moxifloxacin, Mycophenolate Mofetil, Mycophenolic Acid, Nafarelin, Neratinib, Nilotinib, Norfloxacin, Nortriptyline, Octreotide, Ofloxacin, Ondansetron, Osilodrostat, Osimertinib, Oxaliplatin, Ozanimod, Paliperidone, Panobinostat, Pasireotide, Pazopanib, Pentopril, Perindopril, Phenytoin, Pimavanserin, Piperaquine, Pitolisant, Polyethylene Glycol 3350, Ponesimod, Posaconazole, Procainamide, Prochlorperazine, Promethazine, Propafenone, Protriptyline, Quetiapine, Quinapril, Quinidine, Quinine, Raltegravir, Ramipril, Ranolazine, Ribociclib, Rilpivirine, Selpercatinib, Senna, Sertraline, Sevoflurane, Siponimod, Sodium Picosulfate, Sodium Polystyrene Sulfonate, Solifenacin, Sorafenib, Sotalol, Spirapril, Spironolactone, St John's Wort, Sulpiride, Sunitinib, Tacrolimus, Telavancin, Telithromycin, Temocapril, Tetrabenazine, Toremifene, Trandolapril, Trazodone, Triamterene, Triclabendazole, Trifluoperazine, Trimipramine, Triptorelin, Vandetanib, Vardenafil, Vemurafenib, Vinflunine, Vismodegib, Voclosporin, Voriconazole, Zofenopril, and Zuclopenthixol.

Additionally, antacids containing aluminum and/or magnesium, as well as other laxatives, may also interact with Kristalose. These interactions can alter how the medications work or increase the risk of side effects. Always consult your healthcare provider before starting or stopping any medication.