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The following information outlines critical safety considerations and warnings for the use of this medication. It is essential to read these details thoroughly and seek advice from your healthcare provider if you have any questions or concerns.

• Skin Irritation: Tretinoin may lead to redness, dryness, pain, and irritation at the application site. It is advised not to use the medication on sunburned skin or areas affected by eczema as these are more susceptible to irritation. Individuals with sensitive skin, eczema, or those exposed to extreme weather conditions should exercise caution.

• Sun Sensitivity: Tretinoin increases the skin's sensitivity to sunlight, both natural and artificial, such as from sunlamps. This heightened sensitivity can result in easier sunburn, potentially increasing the risk of premature skin aging and skin cancer. Individuals with high sun exposure, those whose skin burns easily, or who live in hot climates and work outdoors should take extra precautions.

• Fish Allergy Caution (specific to Atralin gel and generics): Certain tretinoin products, like Atralin gel and its generic versions, contain fish proteins. If you have a fish allergy, use this medication with caution. Should you experience a red, itchy rash (hives), discontinue use and inform your healthcare provider, as you may need to stop using tretinoin.

Please note that there are no specific contraindications listed for this medication. Always follow your healthcare provider's guidance when using tretinoin.

When using Atralin (tretinoin) gel for acne treatment, it's important to be aware of potential interactions with other products and conditions that could affect your skin's health and the effectiveness of the treatment.

Interactions with Other Topical Products:

Avoid using Atralin alongside skin products containing Benzoyl Peroxide, sulfur, Resorcinol, or Salicylic Acid unless directed by your doctor. Combining these substances can increase skin irritation.

Sun Exposure:

Atralin can make your skin more sensitive to sunlight. To minimize the risk of sunburn, limit your time in the sun, avoid tanning beds, and use a sunscreen with at least SPF 15 when exposure is unavoidable.

Skin Conditions:

If you have eczema or sunburned skin, use Atralin with caution, as it may cause severe irritation in these conditions.

Allergies:

Atralin contains soluble fish proteins. If you have a known sensitivity or allergy to fish, consult your healthcare provider before using this product.

General Precautions:

To reduce the risk of skin irritation while using Atralin:

• Gently wash the treated area with a mild, non-medicated soap and pat it dry.

• Avoid washing the treated skin too often or scrubbing the affected area.

• Steer clear of contact with lime peels, as they can cause additional irritation.

Always inform your healthcare provider about all medications and skin products you are using to ensure safe and effective treatment with Atralin.