Silver Sulfadiazine

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silver sulfadiazine

Silver sulfadiazine is a prescription antibiotic cream specifically designed to prevent and treat serious skin infections resulting from second- or third-degree burns. By inhibiting bacterial growth, it reduces the risk of infection spreading to adjacent skin or entering the bloodstream, which could lead to severe complications like sepsis. This medication should be applied once or twice daily after cleaning the wound, and it works by damaging the protective layers of bacteria, effectively killing them. Although generally safe, silver sulfadiazine can cause side effects such as rash or skin redness, and in rare cases, serious allergic reactions. It is important to note that this medication should not be used on premature babies or newborns within their first two months due to potential serious side effects. Always consult a healthcare professional before starting any new treatment.
Our Silvadene coupons are free to use. You can print the coupon, email it to yourself, or receive the Silvadene coupon via text message. To get your free discount, show the pharmacist your Silvadene savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Silvadene prices will update based on your prescription needs. Above our Silvadene coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Silvadene savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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25GM of 1%, Silver Sulfadiazine (1 Bottle)

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CVS

$19.43

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Walgreens

$2.00

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Walmart

$6.00

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Rite Aid

$9.96

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CVS

$19.43

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Silvadene dosage forms

The average cost for 1 Bottle of Silvadene (silver sulfadiazine) at 25GM of 1% is $19.43 with a free coupon. This is 82.33% off the average retail price of $23.6
DosageQuantityPrice fromPer unit
25GM of 1%1 Bottle$19.43$19.43

Silvadene Warnings

This medication has important safety information that you need to be aware of. Please read the following warnings and consult your healthcare provider if you have any questions or concerns.

  • Severe Allergic and Skin Reactions: While rare, severe allergic reactions to silver sulfadiazine (SSD) can occur, including life-threatening conditions such as Stevens-Johnson syndrome (SJS) or anaphylaxis. If you experience symptoms like painful blisters, hives, a widespread rash, swelling of the lips or tongue, or breathing difficulties, seek emergency medical help immediately by calling 911. Inform your healthcare provider if you have a known allergy to sulfa medications before starting SSD.

  • Changes in Blood Cell Levels: Although uncommon, silver sulfadiazine (SSD) may cause blood-related issues, such as low blood cell levels. Symptoms can include weakness, dizziness, fatigue, and unusual bleeding. Contact your healthcare provider if you experience any of these symptoms.

  • Risk of Fungal Infections: Prolonged use of silver sulfadiazine (SSD) may lead to fungal infections at the application site. If you notice increased skin redness, itching, or burning, inform your healthcare provider promptly. Your provider will monitor your condition if long-term use is necessary.

Contraindications: This medication should not be used in the following situations due to potential serious health risks. Consult your healthcare provider if any of these apply to you:

  • Pregnant individuals nearing their due date.
  • Infants less than 2 months old.

Always communicate with your healthcare provider about your health status and any other medications you are taking to ensure safe use of this medication.

Silvadene Side Effects

When using this medication, some individuals may experience side effects, which can vary in severity. Commonly, there might be mild discomfort such as pain, burning, or itching of the treated skin. Temporary changes in skin color, such as blue or gray discoloration, may also occur, as well as a mild rash or skin redness. These side effects are typically not severe, but if they persist or worsen, it's advisable to consult a healthcare provider for reassurance and guidance.

In rare cases, more serious side effects can occur and should be addressed immediately. These include signs of infection like a persistent sore throat, fever, or chills, as well as symptoms indicating potential anemia such as unusual tiredness, rapid breathing, or a fast heartbeat. Additionally, signs of kidney or liver problems, such as changes in urine color or amount, persistent nausea, vomiting, or yellowing of the skin or eyes, require prompt medical attention.

An allergic reaction, while uncommon, is a serious concern. Symptoms may include a rash, itching or swelling, particularly of the face, tongue, or throat, severe dizziness, and breathing difficulties. Should any of these symptoms develop, seek urgent medical care. Always be vigilant for any side effects not listed here, and discuss them with your healthcare provider to ensure your safety and well-being.

Silvadene Interactions

Some medications and substances can interact with Silver sulfadiazine (SSD). It is important to inform your doctor and pharmacist about any other medications, supplements, or skin products you are using.

Certain skin products containing sodium sulfacetamide, as well as enzyme products like Collagenase, Papain, and trypsin, may interact with SSD. Additionally, an ingredient in some forms of this medication, Propylene Glycol, might affect lab tests, potentially leading to inaccurate results. Ensure that your healthcare providers and lab technicians are aware you are using SSD to prevent any test misinterpretations.

Silver sulfadiazine (SSD) should not be used with Methenamine, as this combination is not recommended. If you are using Methotrexate, your doctor might adjust your medication regimen since combining it with SSD is typically not advised unless necessary. Furthermore, when SSD is used along with aminolevulinic acid, there may be an increased risk of side effects, but in some cases, using both could be beneficial. Your doctor may need to adjust the dosages or the frequency of these medications.

Silvadene FAQs
Why is Silvadene no longer recommended?

Silvadene (silver sulfadiazine) is not recommended as frequently as it once was due to concerns about potential side effects and the availability of more effective alternatives. It can delay wound healing, cause allergic reactions, and lead to the development of resistant bacteria. Additionally, newer treatments may offer better outcomes with fewer complications. It is important for patients to consult with their healthcare provider for the most appropriate treatment options for their specific condition.

Silvadene cream is used to treat and prevent infections in patients with second- and third-degree burns. It helps to reduce the risk of infection and promote healing in the affected areas.

Silvadene (silver sulfadiazine) is not available over the counter. It requires a prescription from a healthcare provider.

The choice between silver sulfadiazine and Neosporin depends on the specific condition being treated. Silver sulfadiazine is commonly used for preventing and treating infections in burn wounds due to its broad antimicrobial properties. Neosporin, on the other hand, is typically used for minor cuts, scrapes, and burns to prevent infection. A healthcare provider should be consulted to determine the most appropriate treatment based on the type and severity of the wound.

Doctors may recommend using plain petroleum jelly or an antibiotic ointment like bacitracin as alternatives to Neosporin. These options can help keep wounds moist and promote healing while minimizing the risk of allergic reactions that some individuals experience with Neosporin. It's always best to consult with a healthcare professional for personalized advice.