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When considering the use of Aliskiren (Tekturna), it is crucial to be aware of the important safety information and potential risks associated with this medication. Below are key points to consider and discuss with your healthcare provider:

• Pregnancy Risk: Aliskiren (Tekturna) may cause severe harm or potentially fatal effects to an unborn baby if taken during pregnancy. It is imperative to avoid pregnancy while on this medication. If you become pregnant or suspect you may be pregnant, discontinue use immediately and consult with your healthcare provider to discuss safe alternatives and reliable birth control methods.

• Allergic Reactions: This medication can cause serious allergic reactions, including anaphylaxis and angioedema, which are characterized by swelling of the face, lips, throat, or extremities, and breathing difficulties. Seek emergency medical attention if you experience any of these symptoms.

• Blood Pressure Effects: Aliskiren (Tekturna) can lower blood pressure, leading to dizziness or lightheadedness, particularly when starting the medication. These effects may be more pronounced if you are dehydrated, have low salt levels, or are on other blood pressure medications.

• High Potassium Levels: The medication can increase potassium levels in the body, which may lead to heart rhythm issues. The risk is heightened if you have kidney problems or are taking other medications that raise potassium levels. Regular blood tests are essential to monitor potassium levels.

• Kidney Function: Aliskiren (Tekturna) can impact kidney function, potentially causing kidney failure. Those with pre-existing kidney issues or taking medications that affect the kidneys should undergo regular kidney function tests. Reduced urination or dark urine should be reported to a healthcare provider promptly.

• Drug Interactions: Avoid using Aliskiren (Tekturna) in conjunction with ACE inhibitors or ARBs, particularly if you have diabetes, as this combination can lead to severe kidney damage, high potassium levels, and dangerously low blood pressure. Additionally, do not use this medication with cyclosporine or itraconazole, as these drugs can significantly increase Aliskiren levels in the body, leading to serious side effects.

• Contraindications: Aliskiren (Tekturna) should not be used in children under 2 years of age or individuals with diabetes who are taking ACE inhibitors or ARBs due to the risk of adverse health effects. Always disclose your complete medical history and current medications to your healthcare provider before starting this medication.

It is vital to adhere to these guidelines and consult your healthcare provider for personalized advice and regular monitoring while using Aliskiren (Tekturna).

When taking this medication, you might experience some common side effects such as dizziness, lightheadedness, cough, diarrhea, stomach pain, indigestion, or acid reflux. These effects are generally mild, but if they persist or worsen, it's advisable to consult your healthcare provider. To minimize dizziness and lightheadedness, try standing up slowly from sitting or lying down positions.

However, there are rare but more severe side effects that warrant immediate medical attention. These include symptoms of a very serious allergic reaction, such as rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. Additionally, be alert for signs of high potassium levels, which may present as muscle weakness, slow or irregular heartbeat, nausea, chest pain, tingling or numbness. Kidney issues are another serious concern, and symptoms can include a noticeable change in urination, fatigue, confusion, or swelling in the feet or ankles.

In extremely rare instances, seizures may occur. It's important to be vigilant and seek urgent medical care if you experience any of these severe side effects. Always remember, while many individuals do not experience significant issues with this medication, staying informed and attentive to your body's responses is crucial for safe use.

Aliskiren, also known as Tekturna, can interact with a variety of medications, and it's important to inform your doctor and pharmacist about all drugs and supplements you are currently taking, whether they are prescription, over-the-counter, vitamins, or herbal supplements.

Certain medications can increase potassium levels in your blood when taken with aliskiren. These include ACE inhibitors like benazepril and lisinopril, ARBs such as candesartan and losartan, and birth control pills containing drospirenone.

Additionally, some drugs may alter how aliskiren is eliminated from your body, impacting its effectiveness. Medications such as itraconazole, cyclosporine, and quinidine are known to have this effect.

Moreover, some products, especially those for cough and cold, diet aids, and NSAIDs like ibuprofen and naproxen, may increase your blood pressure. It's vital to discuss with your pharmacist how to safely use these products.

In some cases, using aliskiren with other specific medications is not recommended due to potential interactions. These include azilsartan, benazepril, candesartan, lisinopril, losartan, and many others. If aliskiren must be used with these drugs, your doctor might adjust the dosage or frequency of use.

Similarly, combining aliskiren with certain other medications, such as capmatinib or simeprevir, is usually not recommended unless necessary. Your healthcare provider may decide to modify how you take one or both medications if they are prescribed together.

Lastly, some combinations, like those with furosemide or rifampin, may increase the risk of side effects, yet could be required for your treatment. In such cases, your doctor will carefully manage the dosages to ensure safety and efficacy. Always follow your healthcare provider's guidance when using aliskiren with other medications.