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You might experience dizziness, drowsiness, lightheadedness, loss of appetite, or diarrhea while taking this medication. These are common side effects and usually not a cause for concern. However, if they persist or worsen, it's a good idea to discuss them with your healthcare provider. To minimize dizziness and lightheadedness, try rising slowly from sitting or lying down positions.

This medication can also lead to dehydration and an imbalance in electrolytes. Be mindful of symptoms such as an unusually dry mouth, persistent thirst, muscle cramps or weakness, irregular heartbeat, or confusion, and consult your doctor promptly if they occur.

There are more serious side effects to be aware of, though they are less common. These include joint pain, breast pain or enlargement in men, easy bruising or bleeding, fainting, signs of kidney issues like changes in urination, and liver problems indicated by nausea, persistent vomiting, dark urine, abdominal pain, or yellowing of the skin or eyes. A decrease in vision or eye pain should also be addressed immediately.

In rare cases, severe allergic reactions can occur. If you notice a rash, itching, swelling—especially on the face, tongue, or throat—severe dizziness, or difficulty breathing, seek medical attention right away. While this guide outlines major side effects, if you observe any other unusual symptoms, reach out to your healthcare provider for advice.

Certain medications can interact with this drug. These include dofetilide, lithium, and others that might affect potassium levels, like eplerenone, tacrolimus, cyclosporine, and birth control pills with drospirenone. Additionally, diuretics such as amiloride and triamterene, ACE inhibitors such as benazepril and captopril, and angiotensin receptor blockers like losartan and valsartan can also interact.

Some products may contain ingredients that could increase your blood pressure or exacerbate heart failure. It is important to inform your pharmacist about all the products you are using. They can advise you on safe usage, particularly with cough-and-cold medications, weight loss products, or NSAIDs like ibuprofen and naproxen.

This medication might also affect certain laboratory tests, such as parathyroid or protein-bound iodide tests, leading to inaccurate results. Ensure that all your healthcare providers are aware that you are taking this medication.