Trazodone

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generic Raldesy

Trazodone is a medication primarily used to treat major depressive disorder (MDD) in adults. Although not the first choice for depression, it may also be prescribed off-label for insomnia. It is taken orally, usually once or several times a day, based on your specific needs. Trazodone belongs to a class of drugs known as atypical antidepressants and functions as a serotonin antagonist and reuptake inhibitor (SARI). It helps to balance serotonin levels in the brain, which can positively impact mood regulation. Common side effects may include drowsiness, dry mouth, and dizziness. If you have questions about trazodone, consult with your healthcare provider for personalized medical advice.
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100MG, Trazodone (30 Tablets)

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CVS

$18.87

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Rite Aid

$5.29

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Walgreens

$8.86

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Albertsons

$10.54

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CVS

$18.87

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Trazodone dosage forms

The average cost for 30 Tablets of Trazodone (generic Raldesy) at 100MG is $8 with a free coupon. This is 34.63% off the average retail price of $23.1
DosageQuantityPrice fromPer unit
100MG30 Tablets$8$0.27
150MG30 Tablets$8$0.27
50MG30 Tablets$4.54$0.15
300MG30 Tablets$32.85$1.09

Trazodone Warnings

Antidepressants, including trazodone, are prescribed for treating depression and other mental health disorders. While they can offer significant benefits, they also come with potential risks, especially for younger individuals. It is crucial to discuss these risks and benefits with a healthcare provider, particularly for those under 25 years old. Here are important safety considerations and warnings regarding the use of trazodone:

  • Worsening Depression and Suicidal Thoughts: Antidepressants may sometimes exacerbate depression or increase suicidal thoughts, particularly in individuals 24 years old or younger. This risk is heightened in the initial months of treatment and during dosage changes. Immediate medical attention is necessary if symptoms such as suicidal thoughts, anxiety, panic attacks, irritability, or restlessness occur.

  • Serotonin Syndrome Risk: Trazodone can lead to a rare but severe condition called serotonin syndrome, especially when used with other medications that increase serotonin levels. Symptoms include fast heart rate, sweating, muscle stiffness, fever, and confusion. Seek emergency medical help if these symptoms arise.

  • Heart Rhythm Concerns (QT Prolongation): Trazodone may cause life-threatening heart rhythm issues, known as QT prolongation. Risk factors include electrolyte imbalances, existing heart conditions, or concurrent use of other heart-affecting medications. Regular heart monitoring may be necessary, and emergency help should be sought if symptoms like chest pain or fainting occur.

  • Cognitive Impairment and Drowsiness: This medication may cause significant drowsiness or impair cognitive function. Avoid activities requiring alertness until you know how trazodone affects you. Consult your healthcare provider if excessive sleepiness persists.

  • Hypotension and Dizziness: Trazodone may cause low blood pressure, leading to dizziness or fainting. Rise slowly from sitting or lying positions to mitigate this risk, and consult a healthcare professional if dizziness continues.

  • Increased Bleeding Risk: The risk of severe bleeding may rise if trazodone is taken with blood-thinning medications. Be alert for unusual bleeding or bruising and seek medical advice if necessary.

  • Prolonged Erection (Priapism): Rarely, trazodone can cause prolonged and painful erections. Seek immediate medical attention if an erection lasts longer than four hours.

  • Glaucoma Risk: Trazodone may trigger or worsen angle-closure glaucoma. Regular eye examinations are recommended, and any vision changes should be reported to a healthcare provider.

  • Hyponatremia (Low Sodium Levels): This medication may cause low sodium levels in the blood. Symptoms such as confusion, headache, or difficulty concentrating require urgent medical evaluation.

  • Withdrawal Symptoms: Do not abruptly discontinue trazodone without consulting a healthcare provider, as withdrawal symptoms like anxiety or seizures may occur. A gradual dose reduction is recommended.

Contraindications:

  • Avoid trazodone if you are currently taking or have recently taken MAOIs, linezolid, or methylene blue within the last 14 days, as serious health risks may ensue.

Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.

Trazodone Side Effects

Common side effects:

  • Sleepiness
  • Dry mouth
  • Dizziness
  • Headache
  • Blurred vision
  • Nausea or vomiting

Less common but important to monitor:

  • Constipation
  • Fainting
  • Fatigue
  • Nervousness
  • Confusion
  • Changes in blood pressure
  • Changes in weight

Serious side effects:

  • Suicidal thoughts
  • Serotonin syndrome
  • Abnormal heart rhythms
  • Severe bleeding
  • Low blood sodium levels
  • Painful or prolonged erection
  • Severe allergic reactions
  • Vision changes

Trazodone Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • MAO inhibitors

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

  • Drugs affecting trazodone metabolism (e.g., azole antifungals, HIV protease inhibitors, macrolide antibiotics)
  • Serotonin-enhancing drugs (e.g., SSRIs, SNRIs, St. John's wort, MDMA)

Interactions with low risk that usually do not require a change in therapy:

Trazodone FAQs
What does trazodone do to a person?

Trazodone is primarily used to treat major depressive disorder. It can help improve mood, appetite, and energy levels while reducing anxiety and insomnia related to depression. Additionally, trazodone is sometimes prescribed off-label for insomnia due to its sedative effects. It works by affecting the balance of certain chemicals in the brain, particularly serotonin.

Trazodone is not primarily classified as a sleeping pill, but it is often prescribed off-label to help with sleep due to its sedative effects. It is an antidepressant that can aid in improving sleep quality, particularly in individuals with depression-related insomnia. However, its effectiveness and strength as a sleep aid can vary from person to person. It is important for individuals to consult with their healthcare provider to determine if trazodone is appropriate for their specific needs.

Trazodone is often used in dogs to manage anxiety and stress-related behaviors. It can help with conditions such as separation anxiety, noise phobias, and general anxiety. Trazodone works by affecting serotonin levels in the brain, which can have a calming effect on the dog. It is important for a veterinarian to determine the appropriate dosage and monitor the dog for any potential side effects.

Xanax (alprazolam) and trazodone are both medications used to treat different conditions, but they belong to different drug classes and work in distinct ways. Xanax is a benzodiazepine primarily used to treat anxiety and panic disorders. It works by enhancing the effects of a neurotransmitter called GABA in the brain, which has a calming effect.Trazodone, on the other hand, is an antidepressant that is often used to treat major depressive disorder and is also commonly prescribed for insomnia due to its sedative properties. It works by affecting the balance of serotonin in the brain.In summary, Xanax is mainly used for anxiety and panic disorders, while trazodone is used for depression and sleep issues. They have different mechanisms of action and belong to different drug classes.

The appropriate dosage of trazodone for a dog can vary based on the dog's weight, health status, and specific needs. It is crucial to consult a veterinarian to determine the correct dosage and ensure it is safe for the dog. The veterinarian will provide guidance tailored to the individual dog's situation.