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This medication is not intended for use in weight loss, as standard doses are ineffective for this purpose, and higher doses can lead to serious or potentially fatal side effects, particularly when combined with diet pills.

Please review the following important safety information regarding this medication, and consult your healthcare provider with any concerns:

• Not for Weight Loss: Levothyroxine (Synthroid) should not be used for weight loss. It is neither safe nor effective for this use. High doses, especially when combined with other weight loss medications, can result in serious or fatal consequences.

• Heart Issues: Excessive intake of levothyroxine (Synthroid) may lead to heart problems, particularly in older adults or individuals with existing heart conditions. Seek immediate medical attention if you experience symptoms such as rapid or irregular heartbeat, chest pain, or breathing difficulties. Your healthcare provider may need to adjust your dosage or discontinue the medication if new heart problems arise.

• Adrenal Crisis: In rare instances, individuals with both low thyroid and adrenal hormone levels, such as those with Addison's disease, should inform their provider. It is crucial to treat adrenal hormone levels before addressing thyroid issues, as initiating thyroid hormone treatment first can exacerbate adrenal hormone deficiencies. If you experience symptoms like persistent fatigue, stomach pain, dizziness, weakness, or vomiting, seek medical help promptly.

• Diabetes Management: Levothyroxine (Synthroid) can elevate blood sugar levels, particularly when starting the medication or increasing the dosage. If you have diabetes, your provider may need to adjust your diabetes medications. Monitor your blood sugar as advised and consult your provider if your levels are elevated.

• Bone Health: Long-term use of levothyroxine (Synthroid) can weaken bones, especially with high doses. Postmenopausal females are at higher risk. To minimize this risk, your provider will regularly monitor your thyroid levels to ensure you are on the lowest effective dose. Engage in regular exercise, maintain a bone-healthy diet, and limit alcohol consumption.

Contraindications:

• Uncorrected Adrenal Insufficiency: Do not use this medication if you have untreated adrenal insufficiency, as it may pose significant health risks. Consult your healthcare provider if this condition applies to you.

While taking this medication, some individuals may experience hair loss during the initial months of treatment. This side effect is generally temporary and should lessen as your body adjusts. Common mild side effects can include nervousness, irritability, trouble sleeping, tremors, headache, and increased sweating. More mild reactions such as changes in appetite, weight loss, vomiting, diarrhea, and sensitivity to heat may also occur.

In some cases, patients might experience symptoms like irregular heartbeat, chest pain, shortness of breath, leg cramps, muscle weakness, and changes in their menstrual period. These are typically mild, but if they persist or worsen, consulting with a healthcare provider can provide reassurance and guidance.

However, there are more serious side effects that require immediate medical attention. These include severe symptoms of high thyroid hormone levels such as fast or pounding heartbeat, seizures, bone pain, or easily broken bones. Additionally, signs of heart failure like trouble breathing, swelling in the hands, ankles, and feet, or signs of a heart attack such as dizziness, cold sweat, or chest pain need urgent medical care.

A very serious allergic reaction is rare but can occur. Symptoms to watch for include rash, severe dizziness, itching or swelling, particularly of the face, tongue, or throat, and difficulty breathing. Immediate medical help should be sought if these occur. Always consult a healthcare provider if you notice any other side effects not listed here.