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Sertraline

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generic Zoloft

Sertraline, commonly known by the brand name Zoloft, is a medication primarily used to treat a variety of mental health conditions. These include major depressive disorder, panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. As a selective serotonin reuptake inhibitor (SSRI), sertraline functions by increasing serotonin levels in the brain, which helps regulate mood and anxiety. It is typically taken orally once a day and is available in both tablet and liquid forms. Common side effects may include nausea, diarrhea, and dry mouth. Patients are advised to avoid alcohol while taking sertraline, as it may exacerbate these side effects. Always consult with a healthcare professional before starting any new medication.
Our coupons are free to use. Before paying, show the pharmacist your Sertraline savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Sertraline prices will update based on your prescription needs. Above our Sertraline coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Sertraline at the lowest price with our prescription discount card.

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100MG, Sertraline (30 Tablets)

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CVS

$19.23

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Rite Aid

$5.07

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Albertsons

$10.23

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Walgreens

$20.24

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$19.23

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Sertraline dosage forms

The average cost for 30 Tablets of Sertraline (generic Zoloft) at 100MG is $8 with a free coupon. This is 11.70% off the average retail price of $68.4
DosageQuantityPrice fromPer unit
100MG30 Tablets$8$0.27
50MG30 Tablets$3.82$0.13
25MG30 Tablets$8$0.27

Sertraline Warnings

When using antidepressant medications, including sertraline (Zoloft), it is crucial to be informed about potential risks and precautions. Below are important safety warnings and guidelines for use:

  • Worsening Depression and Suicidal Thoughts: Antidepressants may lead to a worsening of depression or the emergence of suicidal thoughts, especially in individuals under 25 years of age. This risk is heightened during the initial months of treatment and when adjusting the dosage. If you or someone around you notices any signs of suicidal thoughts, unusual behavior, or mood changes like anxiety, irritability, or restlessness, seek medical assistance immediately.

  • Serotonin Syndrome: There is a risk of developing serotonin syndrome, a potentially life-threatening condition, when taking sertraline (Zoloft), particularly if combined with other medications that increase serotonin levels. Symptoms include rapid heart rate, sweating, confusion, and muscle stiffness. Prompt medical help is necessary if these symptoms occur.

  • Risk of Bleeding: The use of sertraline (Zoloft) may elevate the risk of significant bleeding, especially if taken alongside blood-thinning medications such as aspirin or warfarin. Look out for unusual bruising, bleeding, or dark stools, and contact a healthcare provider if these occur.

  • Bipolar Disorder Considerations: Antidepressants like sertraline (Zoloft) can trigger manic episodes in individuals with bipolar disorder. It is important to assess the risk of bipolar disorder before starting treatment, and to monitor for any behavioral changes such as racing thoughts or increased talkativeness.

  • Glaucoma Risk: Sertraline (Zoloft) can exacerbate or induce angle-closure glaucoma. Regular eye check-ups are advised, and any changes in vision should be promptly reported to a healthcare professional.

  • Heart Rhythm Concerns: The medication may lead to QT prolongation, affecting heart rhythm. This risk is compounded by factors such as electrolyte imbalances or concurrent use of other heart-affecting medications. Regular heart monitoring may be necessary, and immediate medical attention is required if symptoms like chest pain or fainting occur.

  • Low Sodium Levels: Sertraline (Zoloft) can cause hyponatremia, particularly in the elderly or those on diuretics. Symptoms of low sodium, such as confusion or headaches, demand urgent medical evaluation.

Contraindications: This medication should not be used if you are taking or have recently taken MAO inhibitors, linezolid, methylene blue, pimozide, or disulfiram (for the liquid form of sertraline). Consult a healthcare provider if any of these apply to you.

It is essential to discuss any concerns with a healthcare professional and keep them informed of all medications you are taking to ensure safe and effective treatment.

Sertraline Side Effects

Common side effects:

  • nausea
  • diarrhea
  • difficulty sleeping
  • dry mouth
  • drowsiness
  • loss of appetite
  • increased sweating
  • upset stomach

Less common but important to monitor:

  • irregular heartbeat
  • tremors
  • changes in vision
  • decreased interest in sex
  • changes in sexual ability
  • muscle cramps or weakness
  • unusual weight loss

Serious side effects:

  • serious allergic reactions
  • serotonin syndrome
  • severe bleeding
  • suicidal thoughts or behavior
  • painful or prolonged erection

Sertraline Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Interactions with low risk that usually do not require a change in therapy:

  • Alcohol
  • Marijuana (cannabis)
  • Antihistamines (such as Cetirizine, diphenhydramine)
  • Drugs for sleep or anxiety (such as Alprazolam, Diazepam, Zolpidem)
  • Muscle relaxants
  • Opioid pain or cough relievers (such as codeine, hydrocodone)
  • Aspirin
Sertraline FAQs
Does sertraline help with anger?

Sertraline, an antidepressant in the selective serotonin reuptake inhibitor (SSRI) class, is primarily used to treat depression and anxiety disorders. While it is not specifically approved for managing anger, some individuals may experience a reduction in irritability and anger as their overall mood and anxiety symptoms improve. It is important for individuals to consult with their healthcare provider to determine the most appropriate treatment for their specific symptoms.

Sertraline is popular because it is an effective and well-tolerated selective serotonin reuptake inhibitor (SSRI) used to treat a variety of mental health conditions, including depression, anxiety disorders, and obsessive-compulsive disorder. It has a favorable side effect profile compared to some other antidepressants, making it a preferred choice for many patients and healthcare providers. Additionally, sertraline has been widely studied and has a long track record of safety and efficacy.

Individuals who should avoid taking sertraline include those with a known allergy to sertraline or any of its components. It is also not recommended for individuals who are taking monoamine oxidase inhibitors (MAOIs) or have taken them in the past 14 days, as this can lead to serious drug interactions. Additionally, those with a history of bipolar disorder, liver disease, or seizure disorders should consult their healthcare provider before starting sertraline. Pregnant or breastfeeding individuals should discuss potential risks and benefits with their doctor.

Medications that may be used to help manage anger outbursts include mood stabilizers such as lithium, certain anticonvulsants like valproate or carbamazepine, and some atypical antipsychotics. Additionally, selective serotonin reuptake inhibitors (SSRIs) may be prescribed if the anger is related to underlying conditions such as depression or anxiety. It is important for individuals to consult with a healthcare provider to determine the most appropriate treatment based on their specific needs and medical history.

Sertraline is typically prescribed for adults and children over the age of 6 for conditions such as depression, anxiety disorders, and OCD. However, it may not be suitable for everyone. Individuals who should avoid taking sertraline include those with a known allergy to the medication, those currently taking monoamine oxidase inhibitors (MAOIs) or pimozide, and those with certain medical conditions such as liver disease or a history of seizures, unless advised by a healthcare provider. Pregnant or breastfeeding individuals should consult their doctor before starting sertraline. It is important for anyone considering sertraline to discuss their full medical history and current medications with their healthcare provider to ensure it is safe for them.