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This medication, used for treating hepatitis C, carries important safety information due to potential risks. It is crucial to review these warnings thoroughly and discuss any concerns with your healthcare provider.

• Hepatitis B Reactivation: Individuals with concurrent hepatitis B and C infections may experience a reactivation of hepatitis B upon starting treatment for hepatitis C. This serious condition can lead to severe liver complications, including death, if not promptly addressed. Prior to initiating treatment, a test for hepatitis B is recommended. Inform your healthcare provider if you have a history of hepatitis B or have previously been treated for it. The risk is higher for those with a history of hepatitis B infection or who are taking immunosuppressive medications.

• Liver Problems: This medication might exacerbate existing liver issues, potentially leading to liver failure or death, especially in individuals with a history of liver conditions such as cirrhosis. It is advised to avoid this medication if you have moderate to severe liver issues. Discuss any liver history with your healthcare provider before starting treatment, as regular liver function tests may be needed. Symptoms of liver damage, such as yellowing of the skin or eyes, nausea, or stomach pain, should prompt immediate medical consultation. The risk is particularly significant for those with a history of liver problems.

• Slow Heart Rate: There have been instances of decreased heart rate and severe cardiac issues in patients taking amiodarone (Pacerone) alongside medications containing sofosbuvir, including this one. These effects can occur shortly after starting the medication or even weeks later, particularly in those also using beta blockers or with existing heart or liver issues. Notify your healthcare provider if you are on or have recently been on amiodarone (Pacerone), as they may consider alternative treatments or closely monitor your heart rhythm. Seek emergency care if you feel faint, dizzy, weak, confused, or experience chest pain or breathing difficulties when taking these medications together. The risk is higher for those taking amiodarone (Pacerone), beta blockers, or with heart or liver problems.

• Interactions with Other Medications: Certain drugs, like St. John's wort and carbamazepine (Tegretol), can reduce the effectiveness of this medication for treating hepatitis C. Always inform your healthcare provider or pharmacist about all medications you are taking, including new ones started during treatment, to ensure safe use and dosage adjustments if necessary.

• Contraindications: Do not use this medication if you are concurrently taking rifampin (Rifadin), as it may pose serious health risks. Consult your healthcare provider for guidance if this applies to you.

In case of an overdose, seek emergency medical assistance immediately. Always adhere to your healthcare provider's instructions and report any unusual symptoms or concerns during your treatment.

When taking this medication, some individuals may experience common side effects, such as headache, tiredness, diarrhea, nausea, and difficulty sleeping. These effects are often mild, but if they persist or worsen, it's advisable to consult a healthcare professional. Additionally, some may experience a sense of weakness or a depressed mood; if these occur, you should seek advice from a healthcare provider, particularly if they become severe.

Rarely, more serious side effects can occur, and they require immediate medical attention. These include signs of an allergic reaction, such as skin rash, itching, hives, or swelling of the face, lips, tongue, or throat, which can lead to trouble breathing. There is also a risk of liver injury, indicated by symptoms such as pain in the right upper abdomen, loss of appetite, persistent nausea, pale stools, dark urine, yellowing of the skin or eyes, and unusual fatigue.

It is important to remain vigilant about any changes in your health while using this medication. If any side effects are noticed, particularly those that are not listed or are severe, it is crucial to contact a healthcare provider promptly.