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This medication comes with several important safety considerations and warnings that you should be aware of. Please review the points below and discuss any concerns with your healthcare provider:

• Ventilator Use: If you are using a ventilator, follow the manufacturer's instructions carefully to prevent particle buildup, which can lead to serious side effects like air pressure buildup in the lungs. Sudden worsening of breathing problems may occur when starting this medication; if this happens, stop treatment and consult your doctor.

• Pregnancy Risks: Ribavirin can harm an unborn baby and should not be used during pregnancy. It remains in the body for up to 6 months after treatment. Avoid pregnancy during this time by using at least two forms of birth control. A negative pregnancy test may be required before starting treatment.

• Anemia Risk: This medication can damage red blood cells, leading to anemia and potentially serious complications like heart attacks, especially if you have pre-existing heart conditions. Report any breathing difficulties or chest pain to your doctor immediately. Blood tests will be conducted before and during treatment to monitor red blood cell levels.

• Combination Therapy: Ribavirin should be used with other antiviral medications to treat chronic hepatitis C effectively; it is not effective on its own.

• Pancreatitis: There is a risk of pancreatitis, characterized by severe abdominal pain, nausea, and vomiting. Consult your healthcare provider if you experience these symptoms.

• Dental Health: Ribavirin may cause dry mouth, leading to dental issues. Brush your teeth twice daily and visit the dentist regularly. Rinse your mouth thoroughly if you vomit after taking the medication.

• Breathing Issues: Serious lung infections can occur, leading to breathing difficulties. Notify your healthcare provider if you experience shortness of breath or chest tightness.

• Drug Interactions: When taken with azathioprine, there is a risk of decreased blood cell count, leading to potentially life-threatening disorders. Regular blood tests are essential.

• Lab Test Changes: Routine blood tests are necessary to monitor the effects of the medication on your blood, liver, and overall health. Checking virus levels is also important to ensure treatment effectiveness.

• Children’s Growth: This medication can cause weight loss and slow growth in children, typically resolving after stopping the medication. Discuss any concerns about growth with your child's doctor.

• Vision Changes: Ribavirin may cause vision problems or worsen existing eye conditions. Eye examinations are recommended before starting treatment, and any vision changes should be reported to your provider.

In cases of overdose, seek emergency medical attention immediately. Always adhere to the prescribed dosage and consult your healthcare provider with any questions or concerns about your treatment plan.

Common side effects:

• Headaches
• Fever
• Muscle aches
• Tiredness or weakness
• Shaking chills
• Nausea
• Vomiting
• Changes in mood
• Irritability
• Decreased appetite

Less common but important to monitor:

• Sweating
• Difficulty concentrating
• Stomach pain
• Infections
• Changes in taste
• Trouble sleeping
• Constipation
• Blurred vision
• Chest soreness
• Redness or irritation of the eyes or eyelids

Serious side effects:

• Severe allergic reactions (rash, itching, swelling of the face, tongue, or throat, severe dizziness, trouble breathing)
• Severe stomach pain radiating to the back
• Signs of pancreatitis
• Serious eye problems potentially leading to vision loss
• Serious blood disorders
• Worsening of breathing difficulties
• Serious lung infections
• Signs of worsening depression
• Thoughts of self-harm or harm to others
• Anemia (unusual tiredness or a fast/pounding heartbeat)

Interactions with high risk of serious adverse effects and should be avoided:

• Didanosine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Abacavir
• Azathioprine
• Mercaptopurine
• Stavudine
• Warfarin
• Zalcitabine
• Zidovudine

Interactions with low risk that usually do not require a change in therapy:

• Interferon Alfa-2b