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Here is important safety information regarding Wynzora (calcipotriene / betamethasone) that you should consider. It is crucial to understand these risks and discuss them with your healthcare provider if any concerns arise.

• High Calcium Levels: This medication may lead to elevated calcium levels in your blood or urine. Your healthcare provider may conduct tests to monitor calcium levels and ensure they remain within a safe range. If your calcium levels become too high, discontinuation of the medication may be necessary until levels stabilize. Discuss any concerns with your healthcare team.

• Changes in Stress Hormone Levels: Betamethasone, a component of Wynzora, is a corticosteroid that mimics cortisol, the body's stress hormone. Prolonged use can result in symptoms of excess cortisol, such as weight gain and increased blood sugar levels. Children are particularly susceptible due to higher absorption rates. Factors increasing risk include using high potency corticosteroids, treating large areas, prolonged treatment duration, concurrent use of multiple corticosteroid products, liver failure, and application on broken skin or under occlusive dressings.

• Allergic Skin Reaction: Some individuals may experience an allergic reaction to the ingredients of Wynzora, which could manifest as a skin rash. If you develop a rash or if your symptoms do not improve, consult your prescriber.

• Cataracts and Glaucoma: Use of Wynzora may increase the risk of cataracts and glaucoma. It is advisable to avoid applying the medication near the eyes. If you experience visual changes, such as blurred vision, eye pain, or tunnel vision, inform your healthcare provider immediately.

By staying informed and vigilant, you can help manage these risks effectively with the assistance of your healthcare team.

When using this medication, some individuals may experience common side effects such as mild itching, burning, redness, or irritation of the skin. These are usually not serious but if they persist or worsen, it is advisable to consult a healthcare provider. Upper respiratory tract infections have also been reported by some users.

Occasionally, users might encounter headaches or irritation at the application site. While these effects are typically manageable, seeking medical advice if they become bothersome is recommended.

On rare occasions, this medication can lead to more serious side effects. These include skin thinning, discoloration, or the appearance of stretch marks, as well as small red bumps known as folliculitis. In some cases, there may be a worsening of psoriasis. There is also a rare risk of increased calcium levels in the blood, which can manifest as mental changes, unexplained constipation, increased thirst, or urination.

Severe allergic reactions are uncommon but require immediate medical attention. Symptoms include rash, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing. Additionally, some users may experience burning, crusting, or peeling of the skin, changes in vision, high blood sugar, or low adrenal gland function, indicated by symptoms such as nausea, vomiting, fatigue, or dizziness.

In rare instances, the medication might be absorbed into the bloodstream, leading to symptoms of excessive corticosteroid exposure like unusual tiredness, weight loss, swelling of ankles/feet, increased thirst or urination, and vision problems. Immediate consultation with a healthcare provider is crucial if such severe side effects occur.