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This medication comes with several important safety warnings that you should carefully review. Please discuss any questions or concerns with your healthcare provider.

• Flammability Risk: Enstilar (calcipotriene / betamethasone) is highly flammable. Avoid exposure to fire, flames, or smoking during application and immediately afterward. Store the can at room temperature, ensuring it does not exceed 120 degrees Fahrenheit.

• Hypercalcemia Risk: This medication may increase calcium levels in your blood or urine. Your healthcare provider may conduct lab tests to monitor these levels. If elevated, you may need to discontinue the medication until levels normalize. Consult your healthcare team if you have any concerns.

• Hormonal Changes: Enstilar contains betamethasone, a corticosteroid, which can elevate stress hormone levels with prolonged use. Symptoms may include weight gain and elevated blood sugar levels, particularly in children, who are at higher risk. Increased risk factors include: using high-potency corticosteroids, applying over large areas, long-term use, using multiple corticosteroid products, liver failure, children, broken skin, and using occlusive dressings.

• Allergic Reactions: Some individuals may experience allergic skin reactions to this medication. If you develop a rash or if your symptoms do not improve, contact your healthcare provider.

• Eye Health Risks: There is an increased risk of glaucoma and cataracts associated with this medication. Avoid contact with your eyes and report any vision changes, such as blurred vision, eye pain, or tunnel vision, to your healthcare team immediately.

Please ensure you follow all guidelines and consult with your healthcare provider for any necessary adjustments or concerns.

When using this medication, some individuals may experience mild side effects such as itching, burning, redness, or irritation at the site of application. These symptoms are common and usually not cause for concern, but if they persist or worsen, it's important to consult a healthcare provider. Some people may also notice skin discoloration or lightening, and in more rare instances, inflamed hair pores (folliculitis) or a worsening of psoriasis may occur.

Infrequently, this medication can lead to increased levels of calcium in the blood, which might manifest as mental or mood changes, unexplained constipation, or increased thirst and urination. In some cases, the medication may be absorbed into the bloodstream, potentially causing symptoms like unusual tiredness, weight loss, headaches, swelling in the ankles or feet, vision problems, or increased thirst and urination. These side effects are more likely to occur in children or when the medication is used over large areas of the skin for extended periods.

A serious allergic reaction to this medication is rare, but immediate medical attention is necessary if you experience symptoms such as a rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing. Other severe side effects that require urgent care include vision changes, high blood sugar symptoms like increased thirst and urination, and signs of low adrenal gland function such as nausea, vomiting, and dizziness. Always contact a healthcare provider if you notice any unexpected side effects.