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Isotretinoin

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isotretinoin

Isotretinoin is an oral medication prescribed for treating severe cystic or nodular acne that has not improved with other treatments like topical benzoyl peroxide, clindamycin, or oral antibiotics such as tetracycline and minocycline. This drug is part of the retinoid class and functions by reducing the production of sebum, the oil in the skin, which helps decrease acne outbreaks and promotes quicker skin renewal. Isotretinoin is typically taken twice a day for a period of 4 to 5 months. Due to the potential risk of serious birth defects, individuals who can become pregnant must undergo regular pregnancy testing and use effective birth control before, during, and after the treatment. Common side effects may include dry lips, dry skin, back pain, and dry eyes. Although no longer sold under the brand name Accutane, isotretinoin is available under other names such as Claravis and Amnesteem, as well as various generic options. Always consult a healthcare professional before starting isotretinoin to ensure it is appropriate for your specific condition.
Our Zenatane coupons are free to use. You can print the coupon, email it to yourself, or receive the Zenatane coupon via text message. To get your free discount, show the pharmacist your Zenatane savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Zenatane prices will update based on your prescription needs. Above our Zenatane coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Zenatane savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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10MG, Isotretinoin (30 Capsules)

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CVS

$73.23

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Walmart

$61.64

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Albertsons

$75.16

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Rite Aid

$78.08

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Walgreens

$154.87

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CVS

$73.23

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Zenatane dosage forms

The average cost for 30 Capsules of Zenatane (isotretinoin) at 10MG is $61.64 with a free coupon. This is 10.02% off the average retail price of $615
DosageQuantityPrice fromPer unit
10MG30 Capsules$61.64$2.05
20MG30 Capsules$61.74$2.06
40MG30 Capsules$61.74$2.06
30MG30 Capsules$61.74$2.06

Zenatane Warnings

Isotretinoin Safety Information and Warnings

This medication carries significant risks and requires careful consideration and adherence to specific guidelines. Below are key safety precautions and warnings associated with isotretinoin:

  • Risks to Unborn Babies: Isotretinoin can cause severe birth defects, miscarriages, and premature births. It is crucial that individuals who can become pregnant do not use this medication. Two reliable forms of contraception must be used for one month before starting isotretinoin, throughout the treatment, and for one month after stopping. Regular pregnancy tests and counseling are necessary. In the U.S., participation in the REMS (iPLEDGE) program is mandatory.

  • Mental Health Concerns: This drug may lead to depression, hallucinations, aggressive behavior, or suicidal thoughts. Individuals with a history of mental health issues should be monitored closely. Immediate consultation with a healthcare provider is advised if mood or behavior changes are noticed.

  • Increased Brain Pressure: Isotretinoin can elevate brain pressure, potentially causing vision loss or, in rare cases, death. Avoid combining with tetracycline antibiotics. Contact your healthcare provider if symptoms like severe headaches, blurred vision, dizziness, nausea, seizures, or stroke occur.

  • Serious Skin Reactions: Life-threatening skin conditions such as Stevens-Johnson syndrome may occur. Seek emergency care if you experience severe rashes, high fever, or breathing difficulties.

  • Pancreatitis Risk: Inflammation of the pancreas may occur. Symptoms include severe stomach pain, nausea, vomiting, swelling, and fever. Contact your healthcare provider immediately if these symptoms appear.

  • Cholesterol and Triglyceride Levels: Isotretinoin can increase cholesterol and triglyceride levels. Regular blood tests are necessary to monitor these levels, and discontinuation of the medication may be required if levels become too high.

  • Hearing Issues: Discontinue use and consult a healthcare professional if you experience hearing loss or ringing in the ears, as these may be permanent.

  • Liver Health: The drug can cause liver inflammation. Pre-treatment and ongoing liver function tests are essential. Symptoms of liver damage include jaundice, right-side abdominal pain, dark urine, and unusual bleeding or bruising.

  • Inflammatory Bowel Disease: Rarely, isotretinoin can cause gastrointestinal inflammation. Stop the medication and inform your healthcare provider if you have stomach pain, rectal bleeding, or severe diarrhea.

  • Bone and Muscle Effects: Muscle weakness and bone pain or fractures may occur, especially in older adults or those with pre-existing bone conditions. Discuss preventive measures with your healthcare provider.

  • Vision Impairments: Isotretinoin can affect eyesight and make wearing contact lenses uncomfortable. Exercise caution when driving, particularly at night, and seek an eye examination if vision changes occur.

Consult your healthcare provider for personalized advice and to understand all risks and benefits of isotretinoin treatment.

Zenatane Side Effects

When taking this medication, you may experience some common side effects that are generally mild and manageable. These include dry lips and mouth, chapped or swollen lips, dry skin or eyes, and nosebleeds. Occasionally, you might notice minor swelling of the eyelids, crusty skin, a headache, cold-like symptoms, or an upset stomach. It's also possible to experience temporary hair thinning, tiredness, and changes in appetite or weight. If these side effects persist or worsen, consulting your healthcare provider is advised.

There are also less common side effects that require attention if they occur. These include back, joint, or muscle pain, changes in vision, and ringing in the ears. Some individuals have reported changes in heartbeat, which should be addressed promptly with a healthcare provider.

Serious side effects, although rare, call for immediate medical care. These include mental or mood changes such as depression or thoughts of suicide, seizures, and symptoms of high pressure in the brain such as severe headaches and vision changes. Additionally, pancreatitis may occur with symptoms like severe stomach pain and persistent nausea or vomiting. Liver damage, indicated by yellowing skin or eyes and dark urine, is another serious concern. In rare cases, serious skin reactions involving pain, blisters, or peeling skin may develop. Should you experience any of these severe symptoms, seek urgent medical attention.

Zenatane Interactions

Isotretinoin can interact with various medications and supplements. It's important to inform your doctor and pharmacist about any drugs or supplements you are currently taking, including prescription, over-the-counter, vitamins, and herbal products. Some notable interactions include:

  1. Antibiotics: Specifically, tetracycline antibiotics such as chlortetracycline, Demeclocycline, doxycycline, and Minocycline. These interactions can affect how isotretinoin works and may require dose adjustments.

  2. Vitamin A and Related Drugs: Isotretinoin is a derivative of vitamin A, so taking additional vitamin A or vitamin A-type drugs like Acitretin or Bexarotene can increase the risk of vitamin A toxicity.

  3. Hormonal Contraceptives: Some hormonal birth control methods, including those containing Ethinyl Estradiol, norgestimate, and levonorgestrel, may have reduced effectiveness when used with isotretinoin. This could lead to spotting or breakthrough bleeding. It's essential to discuss the use of reliable backup contraception with your doctor.

  4. Medications Causing Bone Loss: Drugs such as corticosteroids (e.g., Prednisone) and certain anti-seizure medications like Phenytoin may increase the risk of bone loss when taken with isotretinoin.

If you are prescribed isotretinoin alongside any of these medications, your doctor may adjust the dosage or frequency of use to minimize interactions. Always consult your healthcare provider for guidance tailored to your specific situation.

Zenatane FAQs
What is the greatest side effect of isotretinoin?

The greatest side effect of isotretinoin is its teratogenicity, meaning it can cause severe birth defects if taken during pregnancy. It is crucial for individuals who are pregnant or may become pregnant to avoid using this medication. Additionally, isotretinoin can cause other significant side effects, such as dry skin, lips, and eyes, as well as potential liver function changes and mood alterations. Regular monitoring by a healthcare provider is essential during treatment.

Zenatane is used primarily for the treatment of severe recalcitrant nodular acne that has not responded to other treatments. It is a form of isotretinoin, which is a retinoid, and works by reducing the amount of oil released by oil glands in the skin, helping the skin renew itself more quickly.

Zenatane is not classified as a controlled substance. It is a prescription medication used primarily for the treatment of severe acne.

The cost of Zenatane can vary depending on factors such as the pharmacy, location, dosage, and whether the patient has insurance coverage. It is recommended to check with local pharmacies or the patient's insurance provider for the most accurate and up-to-date pricing information.

Yes, the generic name for Zenatane is isotretinoin.