Alosetron Coupons & Discount Card - Compare Prices Near You
generic Lotronex
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0.5MG, Alosetron (30 Tablets)
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CVS
$42.60
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Rite Aid
$71.33
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Walmart
$81.63
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Albertsons
$116.39
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Walgreens
$248.03
COUPON PRICEAlosetron savings card
Show this card to your pharmacistCVS
$42.60
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019876
LHC07D006D
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Alosetron dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 1MG | 30 Tablets | $72.33 | $2.41 |
| 0.5MG | 30 Tablets | $43.59 | $1.45 |
Warnings
Alosetron has been associated with rare but severe, potentially life-threatening side effects affecting the intestines. These include decreased blood flow to the colon (ischemic colitis) and severe constipation complications. It is crucial to discontinue use immediately and seek medical attention if you experience constipation, new or worsening abdominal pain, or bloody stools/diarrhea. Should constipation persist after stopping alosetron, inform your healthcare provider promptly. Refrain from resuming the medication unless instructed by your doctor.
Alosetron is intended only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) and should only be used by carefully selected patients. For more detailed information on the associated risks and benefits, please consult your doctor or pharmacist.
Alosetron Side Effects
While taking this medication, it's important to be aware of potential side effects, though many individuals experience no serious issues. However, if you encounter severe symptoms like constipation, bloody diarrhea, or increased abdominal pain, seek medical attention immediately.
This medication can occasionally lead to a serious condition known as serotonin syndrome, especially if used with other drugs that elevate serotonin levels. Symptoms to watch for include rapid heartbeat, hallucinations, coordination problems, severe dizziness, nausea, vomiting, diarrhea, muscle twitching, unexplained fever, and unusual agitation. Immediate medical care is crucial if these occur.
Allergic reactions to this drug are rare but can be serious. Seek urgent medical help if you experience symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing.
While this list covers some potential side effects, it's not exhaustive. If you notice any other unusual symptoms, consult your healthcare provider for advice.
Interactions
Keep a comprehensive list of all products you use, including prescription medications, over-the-counter drugs, and herbal supplements, and provide it to both your doctor and pharmacist. One specific drug that can interact with this medication is Apomorphine. Additionally, certain medications, such as Fluvoxamine and viloxazine, can alter how alosetron is removed from your body, potentially impacting its effectiveness.
Taking other medications that cause constipation can increase the risk of severe constipation complications. Discuss with your doctor or pharmacist to ensure the safe use of all your medications.
The likelihood of experiencing serotonin syndrome or toxicity rises if you're using other drugs that boost serotonin levels. This includes street drugs like MDMA (ecstasy), St. John's wort, and some antidepressants, such as SSRIs (like Fluoxetine or paroxetine) and SNRIs (like Duloxetine or Venlafaxine). The risk may be higher when starting or increasing the dosage of these medications.
Who should not take alosetron?
Alosetron should not be taken by individuals with a history of severe constipation, intestinal obstruction, Crohn's disease, ulcerative colitis, diverticulitis, severe hepatic impairment, or a history of ischemic colitis. It is also contraindicated in patients who are unable to understand or comply with the patient-physician agreement required for its use. Additionally, it should not be used by individuals who are allergic to alosetron or any of its components.
What is the drug alosetron used for?
Alosetron is used for the treatment of severe diarrhea-predominant irritable bowel syndrome (IBS) in women who have not responded adequately to conventional therapy.
What is the best drug for IBS?
The best drug for Irritable Bowel Syndrome (IBS) depends on the individual's specific symptoms and needs. Commonly used medications include antispasmodics like hyoscine for cramping, laxatives for constipation, and loperamide for diarrhea. In some cases, low-dose antidepressants or medications like rifaximin and lubiprostone may be prescribed. It is important for individuals to consult with a healthcare provider to determine the most appropriate treatment for their specific condition.
Why was alosetron taken off the market?
Alosetron was initially taken off the market due to concerns about serious side effects, including severe gastrointestinal complications such as ischemic colitis and severe constipation. These adverse effects posed significant health risks to patients, leading to its withdrawal. However, it was later reintroduced with strict prescribing guidelines and a risk management program to ensure patient safety.
Why is alosetron only for females?
Alosetron is primarily prescribed for females because clinical trials have shown that it is more effective in treating irritable bowel syndrome (IBS) with diarrhea predominantly in women. Additionally, the safety profile and risk-benefit analysis were more favorable in females. As a result, the FDA approved alosetron specifically for women with severe IBS-D who have not responded to conventional therapy.