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The following information outlines essential safety concerns and precautions related to the use of Briviact (brivaracetam). It is important to review these carefully and discuss any questions or concerns with your healthcare provider.

• Suicidal Thoughts or Behavior: Brivaracetam, like other antiepileptic drugs, may increase the risk of suicidal thoughts or behavior. Be vigilant for any signs of new or worsening depression or significant mood changes, particularly in the initial months of treatment. Contact your healthcare provider immediately if you notice such changes. In cases of suicidal thoughts, seek emergency assistance by calling 911 or visiting a medical facility promptly.

• Drowsiness and Coordination Issues: This medication may cause drowsiness, fatigue, dizziness, or difficulty with movement and balance. These effects are most likely when starting the medication but can occur at any time during treatment. Avoid activities that require full alertness, such as driving or operating heavy machinery, until you understand how brivaracetam affects you.

• Abnormal Mood and Behavior: Brivaracetam can lead to changes in mood, thoughts, or behavior. Patients may experience irritability, aggression, anxiety, mood swings, depression, withdrawal, hallucinations, paranoia, or psychotic behavior. Report any such changes to your healthcare provider immediately.

• Severe Allergic Reactions: Some individuals may experience severe allergic reactions, including angioedema (swelling of the face, mouth, or throat) and airway constriction, which can impede breathing. If you experience these symptoms, discontinue use and seek immediate medical attention.

• Withdrawal Seizures: Do not abruptly discontinue brivaracetam without consulting your healthcare provider, as this may lead to withdrawal seizures. Your provider will guide you on how to safely taper off the medication if necessary, by gradually reducing the dose over time.

Please remember these guidelines to ensure safe and effective use of Briviact (brivaracetam). Always consult your healthcare provider for personalized advice and support.

When taking this medication, some common side effects might occur, including drowsiness, dizziness, tiredness, and nausea or vomiting. These are generally mild, but if they persist or worsen, it is important to seek medical advice. Other side effects that may be experienced include constipation, balance problems, and irritability. While these are typically less severe, discussing them with a healthcare provider can offer reassurance and guidance.

There are also serious side effects to be aware of, though they are rare. These include severe mood changes, thoughts of self-harm or suicide, and severe allergic reactions, such as difficulty breathing or swelling of the face, mouth, or throat. If any of these symptoms occur, immediate medical attention is necessary. Additionally, loss of coordination and rapid, uncontrollable eye movements are serious side effects that should prompt a consultation with a medical professional.

The occurrence of a very serious allergic reaction is unusual, but if you notice symptoms like rash, itching, or significant swelling, especially on the face or throat, coupled with severe dizziness or trouble breathing, seek medical help right away. Remember, this is not an exhaustive list of side effects. If you notice any other unusual symptoms, contacting a healthcare provider is advisable for further assistance.