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It is important to be aware of potential interactions and precautions when using this medication. Here are some key points to consider:

• Drug Interactions: This medication may interact with digoxin and phosphate binders. It can also reduce the absorption of other medications such as tetracycline antibiotics (e.g., doxycycline, minocycline), bisphosphonates (e.g., alendronate), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin). Additionally, certain medications, like bile acid sequestrants (e.g., cholestyramine, colestipol), mineral oil, and orlistat, can decrease the absorption of vitamin D. It is advisable to space out the administration of these medications as much as possible from calcium/vitamin D doses. Consult your doctor or pharmacist for guidance on appropriate dosing intervals.

• Product Labels: Carefully check the labels of all your prescription, nonprescription, and herbal products, including antacids, laxatives, and vitamins, as they may contain calcium, phosphate, or vitamin D. Seek advice from your pharmacist to ensure safe usage.

• Calcium and Vitamin D: Avoid using medications that contain calcitriol in conjunction with vitamin D since they are very similar.

• Laboratory Tests: This product may affect certain laboratory tests, such as cholesterol tests, potentially leading to inaccurate results. Inform all medical personnel involved in your care that you are using this medication.

By adhering to these guidelines, you can help minimize potential risks and ensure effective use of the medication.

Common side effects:

• Constipation
• Stomach upset

Less common but important to monitor:

• Nausea
• Vomiting
• Loss of appetite
• Unusual weight loss
• Mental or mood changes
• Signs of kidney issues like altered urine output
• Bone or muscle pain
• Headaches
• Increased thirst or urination
• Weakness
• Fatigue
• Rapid or pounding heartbeat

Serious side effects:

• Severe allergic reaction

Interactions with high risk of serious adverse effects and should be avoided:

• Digoxin

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• phosphate binders
• tetracycline antibiotics (such as doxycycline, Minocycline)
• bisphosphonates (such as Alendronate)
• estramustine
• Levothyroxine
• quinolone antibiotics (such as Ciprofloxacin, Levofloxacin)
• bile acid sequestrants (such as Cholestyramine, Colestipol)
• Mineral Oil
• Orlistat

Interactions with low risk that usually do not require a change in therapy:

• Calcitriol