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This medication comes with important safety warnings that must be carefully considered to ensure your well-being. It is vital to consult with your healthcare provider if you have any concerns regarding these risks.

• Severe Allergic Reactions: There is a potential for severe allergic reactions to cefuroxime, which can be life-threatening. Symptoms may include facial swelling, anaphylaxis (e.g., throat closure), shock, hives, rash, red skin, and swelling of the lips or tongue. If you have a history of allergies to antibiotics, particularly penicillin or cephalosporin antibiotics, inform your healthcare provider to assess your risk. Seek immediate medical attention if you experience any of these symptoms while taking cefuroxime.

• Clostridioides difficile Infection: The use of cefuroxime, like all antibiotics, can increase the risk of developing an infection with Clostridioides difficile (C. diff). This occurs because antibiotics can disrupt your gut microbiome, allowing C. diff to proliferate and potentially cause life-threatening diarrhea.

• Drug-Resistant Bacteria Development: It is crucial to take cefuroxime exactly as prescribed. Deviating from the prescribed duration, whether shorter or longer, or using it for inappropriate illnesses can lead to the development of drug-resistant bacteria. Such infections can be severe, life-threatening, and difficult to treat.

The following contraindications must be reviewed before starting this medication, as they may pose serious health risks:

• Severe Allergy to Beta-Lactam Antibiotics: If you have a known severe allergy to beta-lactam antibiotics such as penicillin, amoxicillin (Amoxil), or cephalexin (Keflex), you should avoid taking cefuroxime. Always discuss your medical history with your healthcare provider for a safe treatment plan.

Common side effects:

• swelling at the injection site
• redness at the injection site
• pain at the injection site
• diarrhea
• nausea
• vomiting

Less common but important to monitor:

• low appetite
• stomach pain or cramps
• headaches
• chills
• rash
• itching

Serious side effects:

• allergic reaction (rash, hives, blisters, swelling of the lips or tongue, trouble breathing)
• intestinal issue caused by C. difficile (persistent diarrhea, fever, abdominal pain)
• oral thrush
• yeast infection (white patches in the mouth or changes in vaginal discharge)
• severe dizziness
• trouble breathing