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While taking this medication, you might experience some mild side effects such as nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation. These are common and often temporary. To ease dry mouth, consider using sugarless candy or gum, drinking water, or trying a saliva substitute. Additionally, you may notice a harmless blue-green tint in your urine or stools, which will disappear once you stop the medication.

However, it's important to be aware of more serious side effects. Contact your healthcare provider immediately if you notice symptoms like hot, dry, flushed skin, decreased sweating, eye pain, difficulty urinating, or signs of kidney issues such as changes in urine output or painful urination. These might indicate a serious condition.

Seek urgent medical attention if you experience very severe effects, such as easy bruising or bleeding, black or tarry stools, severe stomach pain, or vomiting that resembles coffee grounds. Additionally, symptoms like persistent nausea, unusual tiredness, dark urine, or yellowing of the eyes or skin could suggest liver problems. Rarely, this drug may trigger a hypertensive crisis, a condition that requires immediate medical intervention. Watch for signs such as severe headache, chest pain, irregular heartbeat, neck stiffness, or sudden vision changes.

Allergic reactions to this medication are uncommon but can be severe. If you notice symptoms like rash, swelling of the face or throat, severe dizziness, or difficulty breathing, seek medical help right away. Always consult your healthcare provider if you notice any side effects that concern you or are not listed here.

This medication can interact with various other products and medications. Some of these include apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium supplements, pramlintide, tetrabenazine, certain treatments for Parkinson's disease (like entacapone, levodopa, tolcapone), some blood pressure medications (such as guanethidine, methyldopa), sulfonamide medications (including sulfa antibiotics like sulfamethoxazole), and sympathomimetic drugs (such as amphetamine and ephedrine). Additionally, products that reduce urine acidity, like antacids, sodium bicarbonate, potassium/sodium citrate, and acetazolamide, can also interact with this medication.

This medication may also raise the risk of bleeding when combined with other drugs that have similar effects, such as anti-platelet medications like clopidogrel and anticoagulants including dabigatran, enoxaparin, and warfarin.

Taking other MAO inhibitors with this medication can lead to a dangerous, potentially fatal interaction. Do not use other MAO inhibitors (such as isocarboxazid, linezolid, metaxalone, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine) while on this medication. Generally, most MAO inhibitors should not be taken for two weeks before and after using this medication. Consult your doctor for guidance on when to start or stop this medication.

Before using this product, inform your doctor about any other drugs you are taking that may lead to very high blood pressure (hypertensive crisis) when used together with this product. This includes herbal supplements like ephedra (ma huang), nasal decongestants such as phenylephrine and pseudoephedrine, stimulants like amphetamines, ephedrine, and epinephrine, and weight-loss aids. This product should not be used alongside these medications. Discuss with your doctor or pharmacist for more information.

If you are also using azole antifungal drugs (such as itraconazole or ketoconazole), take this medication at least two hours after the antifungal.

Review all your prescription and over-the-counter medicine labels carefully, as many contain pain relievers or fever reducers such as aspirin and NSAIDs (ibuprofen, ketorolac, or naproxen). These are similar to salicylate and may increase the risk of side effects if used together. However, if your doctor has prescribed low-dose aspirin to prevent heart attacks or strokes (usually 81-162 milligrams daily), continue taking it unless directed otherwise by your doctor. For more details, speak with your doctor or pharmacist.

Inform your doctor or pharmacist if you are using other products that cause drowsiness, including alcohol, marijuana (cannabis), antihistamines (like cetirizine and diphenhydramine), sleep or anxiety medications (such as alprazolam, diazepam, zolpidem), muscle relaxants, or opioid pain relievers (like codeine).

Check the labels on all your medications (such as allergy or cough-and-cold products) as they may include ingredients that cause drowsiness. Consult your pharmacist to ensure safe usage of these products.

This medication might interfere with certain laboratory tests, potentially leading to incorrect results. Ensure that lab personnel and all of your healthcare providers are aware that you are using this drug.