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This document outlines crucial safety information regarding the use of ciclopirox. It is important to read these warnings and consult with your healthcare provider if you have any questions or concerns.

• Intended Use: Ciclopirox is strictly for application on the skin, nails, or scalp. Avoid contact with eyes, nose, lips, mouth, or vagina as it can lead to irritation. These areas require different treatments for fungal infections. If accidental contact occurs, rinse thoroughly with water and seek medical advice. In the event of accidental ingestion, contact the Poison Control Center at 1-800-222-1222 immediately.

• Allergic Reactions: Mild redness, burning, or stinging may occur with ciclopirox use. However, if you experience severe symptoms such as blistering, oozing, or swelling, discontinue use and consult your healthcare provider. Immediate medical attention is necessary if you experience difficulty breathing after application, as this may indicate a severe allergic reaction.

Please ensure that you follow these guidelines to use ciclopirox safely and effectively.

Common side effects:

• Mild skin redness
• Temporary burning or stinging
• Itching

Less common but important to monitor:

• Dry skin
• Rash
• Acne
• Changes in nail shape or color
• Hair discoloration

Serious side effects:

• Severe allergic reactions characterized by rash, hives, itching, or swelling of the face, lips, tongue, or throat
• Significant burning, itching, crusting, or peeling of the treated skin

Ciclopirox is a topical antifungal medication commonly used to treat various fungal infections of the skin and nails. Due to its minimal absorption into the bloodstream when applied to intact skin, ciclopirox generally has a low risk of interacting with other medications. However, certain considerations should be kept in mind:

• Concurrent Use with Other Topical Products: Applying other medicinal products, cosmetics, or occlusive dressings to the same area as ciclopirox may alter its effectiveness. It's advisable to allow sufficient time between applications to ensure optimal absorption and efficacy.

• Use with Nail Cosmetics: For nail infections, using nail polish or artificial nails during treatment with ciclopirox nail lacquer can interfere with the medication's ability to penetrate the nail and reach the infection site. Patients are typically advised to avoid using nail cosmetics during treatment.

• Systemic Medications: While systemic absorption of ciclopirox is limited, it's important to inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, supplements, and herbal products. This helps in assessing any potential interactions.

• Specific Drug Interactions: Although rare, some interactions have been noted. For instance, using ciclopirox with certain medications like Cyclosporine may increase the risk of liver toxicity. Additionally, ciclopirox can reduce the effectiveness of birth control pills, so alternative contraceptive methods are recommended during treatment.

Always consult your healthcare provider before starting or combining treatments to ensure safety and effectiveness.