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Clobazam carries a potential for abuse and addiction, which can result in overdose and even death. It is crucial to avoid consuming this medication with alcohol or other substances that induce drowsiness or respiratory issues, such as opioid medications like codeine or hydrocodone, as this combination could lead to severe and possibly fatal side effects. To minimize your risk, your healthcare provider will prescribe the lowest effective dose and the shortest treatment duration necessary. Ensure you understand the correct usage of clobazam and are aware of any medications you should avoid while taking it.

In the event of serious side effects such as slow or shallow breathing, unusual lightheadedness, severe drowsiness or dizziness, or difficulty waking up, seek medical attention immediately. Abruptly discontinuing clobazam can result in serious, potentially fatal withdrawal symptoms, particularly if it has been used long-term or in high doses. Your doctor may gradually reduce your dosage to prevent withdrawal. Notify your doctor or pharmacist promptly if you experience withdrawal symptoms such as headaches, insomnia, restlessness, hallucinations or confusion, depression, nausea, or seizures. Withdrawal symptoms can occasionally persist for weeks to months.

When taking this medication, you might experience mild side effects such as drowsiness, dizziness, tiredness, headache, constipation, weight gain, cough, drooling, trouble sleeping, or nausea. These effects are generally manageable, but if they persist or worsen, it's important to consult your healthcare provider.

Be aware of more serious side effects, including changes in mental state or behavior like agitation, nervousness, confusion, memory issues, muscle weakness, loss of coordination, tremors, vision changes, trouble speaking, or painful urination. These require prompt medical attention.

A small number of individuals taking anticonvulsants may encounter depression or suicidal thoughts. It's crucial to seek immediate help if you or those around you notice sudden mood or behavior changes, including signs of depression or self-harm.

Seek urgent medical assistance if you experience severe side effects such as slow or shallow breathing. Clobazam can rarely cause serious skin reactions, especially in the initial weeks of treatment. Symptoms like skin rash, blisters, peeling, itching, or mouth sores need immediate medical attention, as do symptoms of a severe allergic reaction, including fever, swollen lymph nodes, rash, facial swelling, severe dizziness, or difficulty breathing.

This is not an exhaustive list of side effects. If you notice any other unusual symptoms, reach out to your healthcare provider for guidance.

Certain products may have interactions with this medication, including Orlistat and Sodium Oxybate. Additionally, some medications can influence how clobazam is processed in your body, potentially altering its effectiveness. Examples include Fluconazole and Fluvoxamine. Using this medication with others that cause drowsiness or breathing issues might heighten the risk of significant side effects like slow or shallow breathing and severe drowsiness. Inform your doctor or pharmacist if you are using products such as opioid painkillers or cough suppressants (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety drugs (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), or antihistamines (e.g., Cetirizine, diphenhydramine).

Check all medication labels, including those for allergy or cough and cold, as they might contain ingredients that cause drowsiness. Consult your pharmacist for safe usage of these products. This medication might reduce the effectiveness of hormonal birth control methods like pills, patches, or rings, which could result in pregnancy. Discuss with your doctor or pharmacist about using additional reliable birth control methods while on this medication. Also, notify your doctor if you experience any unusual spotting or breakthrough bleeding, as these might indicate that your birth control is not working effectively.