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This document outlines important safety and warning information for the use of betamethasone. It is crucial to understand the potential risks and necessary precautions. Please consult your healthcare provider if you have any questions or concerns regarding this medication.

• Hormonal Changes: Betamethasone may be absorbed through the skin and alter hormone levels, especially with prolonged use, application over large areas, or when the treated area is covered. This can lead to conditions such as adrenal insufficiency, Cushing's syndrome, high blood sugar, and glucosuria (sugar in urine). Children are particularly susceptible to these effects, which may result in slowed growth or delayed weight gain. Hormonal changes can occur during or after treatment; hence, regular monitoring by your healthcare provider might be necessary. Factors increasing risk include using potent corticosteroids, long-term application, use on large or damaged skin areas, liver failure, and pediatric use.

• Eye Health: Certain forms of betamethasone, including augmented formulations and Sernivo spray, can elevate the risk of developing eye conditions such as cataracts and glaucoma. Avoid contact with the eyes, and report any vision changes or blurriness to your healthcare provider immediately.

• Infection Risk: Betamethasone may suppress the immune system and increase the likelihood of skin infections. If an infection occurs, contact your healthcare provider for suitable treatment. Use of betamethasone may be temporarily halted until the infection resolves if necessary.

• Allergic Reactions: There is a possibility of allergic reactions to betamethasone, which could impede skin healing, particularly on cuts or wounds. Notify your healthcare provider if any skin irritation or allergic reaction develops.

Please ensure to adhere to these guidelines and consult with your healthcare professional for personalized advice and monitoring during your treatment with betamethasone.

When using this medication, some common side effects may occur, such as burning, stinging, itching, irritation, dryness, or redness at the application site. These are generally mild and should ease as your body adjusts to the treatment. However, if they persist or worsen, it's advisable to consult a healthcare provider for guidance.

Some users may experience other side effects, including inflamed hair follicles, small acne-like bumps, skin discoloration or lightening, moisture-related skin breakdown, thinning of the skin, stretch marks, skin infections, red rash around the mouth, heat rash, or allergic skin reactions. While these are less common, monitoring their severity is important, and professional advice should be sought if necessary.

Serious side effects, though rare, require immediate medical attention. These include severe allergic reactions characterized by skin rash, fluid-filled blisters, and intense itching, as well as eye issues such as blurry vision or changes in eyesight. Additionally, in rare instances, the medication may be absorbed into the bloodstream, potentially causing unusual tiredness, weight loss, headaches, swelling of the ankles or feet, increased thirst or urination, and vision problems. These effects are more likely in children or when the medication is used over large skin areas or for prolonged periods. Immediate medical care is crucial if these symptoms occur.