Promethazine

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promethazine

Promethazine is a prescription medication primarily used to prevent and treat nausea and vomiting associated with various conditions, including surgery and motion sickness. It is also effective in managing symptoms of allergies, such as a runny nose, watery eyes, and skin reactions like rashes and swelling. Additionally, Promethazine can be used as part of the treatment for severe allergic reactions (anaphylaxis) and to enhance the effects of certain opioid pain relievers like meperidine. The drug works as an antihistamine by blocking histamine, a natural substance in the body that contributes to allergic reactions. It also has anticholinergic properties and blocks dopamine, which helps manage nausea and offers a calming effect. Promethazine can be administered in various forms, including tablets, an oral solution, rectal suppositories, and injections. Notably, Promethazine should not be used in children under the age of 2 due to the risk of severe side effects, such as slow or shallow breathing. Common side effects for older users may include drowsiness and dizziness. Always consult with a healthcare provider before using this medication to ensure it is safe and appropriate for your specific condition.
Our Phenergan coupons are free to use. You can print the coupon, email it to yourself, or receive the Phenergan coupon via text message. To get your free discount, show the pharmacist your Phenergan savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Phenergan prices will update based on your prescription needs. Above our Phenergan coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Phenergan savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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1ML of 25MG/ML, Promethazine (1 Ampule)

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$20.16

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$2.00

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$2.48

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Phenergan dosage forms

The average cost for 1 Ampule of Phenergan (promethazine) at 1ML of 25MG/ML is $1.01 with a free coupon. This is 7.97% off the average retail price of $12.67
DosageQuantityPrice fromPer unit
1ML of 25MG/ML1 Ampule$1.01$1.01
1ML of 50MG/ML1 Ampule$1.01$1.01

Phenergan Warnings

This document provides crucial safety and warning information regarding the use of promethazine. It contains important details about potential risks, precautions, and emergency measures. Review this information carefully and consult your healthcare provider if you have any questions or concerns.

  • Respiratory Risks:

    • Promethazine can cause severe respiratory depression, especially in children under 2 years old and individuals with pre-existing breathing problems like COPD or asthma. Avoid use in children under 2 years and consult your doctor if taking other medications affecting breathing.
    • Seek immediate medical attention if you or your child experiences slow or shallow breathing.
  • Injection Risks:

    • Administer promethazine by intramuscular injection to avoid serious tissue injury, such as gangrene. Do not inject into an artery or under the skin. If you experience burning, pain, redness, or swelling at the injection site, contact your healthcare provider immediately.
  • Sedation and Impaired Function:

    • Promethazine can cause excessive drowsiness, especially when combined with alcohol, opioids, or other sedatives. Avoid driving or operating machinery after taking this medication. Seek medical help if you experience confusion, dizziness, or slurred speech.
  • Exacerbation of Medical Conditions:

    • Promethazine may worsen conditions such as glaucoma, heart problems, enlarged prostate, bladder issues, or liver disease. Discuss all existing health problems with your healthcare provider before starting treatment.
  • Seizure Risk:

    • If you have a history of seizures or are taking medications that lower the seizure threshold, promethazine may increase seizure frequency. Consult your doctor if you fall into this risk category.
  • Infection Risk:

    • Promethazine can lower white blood cell counts, increasing infection risk, especially during cancer treatment. Notify your healthcare team if you develop symptoms like fever or chills.
  • Neuroleptic Malignant Syndrome:

    • This rare but serious condition may occur, especially if taking antipsychotic medications. Symptoms include high fever, rapid heartbeat, and muscle stiffness. Seek medical attention immediately if these occur.
  • Involuntary Movements:

    • Promethazine may cause involuntary muscle movements, particularly in children who are sick and dehydrated or those taking MAOIs. Report any unusual muscle movements to a healthcare provider promptly.

Contraindications:

  • Do not use promethazine in children under 2 years, individuals in a coma, for lower respiratory issues like asthma, if allergic to phenothiazines, or if injection is required into an artery or under the skin.

This information is intended to guide safe usage of promethazine. Always consult your healthcare provider for personalized medical advice.

Phenergan Side Effects

When taking this medication, some individuals may experience common side effects such as drowsiness, dizziness, dry mouth, blurred vision, or confusion. These are typically mild and can often be managed by simple measures like staying hydrated or using sugarless gum for dry mouth. If these effects persist or worsen, it's important to consult with a healthcare provider for guidance.

In some cases, other side effects such as burning sensations, pain, rash, or swelling may occur. While these are generally not severe, it's advisable to contact a healthcare professional if you notice them.

More serious side effects, although rare, demand immediate medical attention. These include symptoms like tremors, nausea, vomiting, uncontrollable body movements, and changes in heart rate. Additionally, severe side effects like a slow or irregular heartbeat, fainting, and neuroleptic malignant syndrome—characterized by fever, muscle stiffness, and severe confusion—are critical and require urgent care.

Allergic reactions to this medication are rare but serious. Symptoms such as rash, itching or swelling, severe dizziness, or trouble breathing warrant prompt medical assistance. Always be vigilant for any unusual symptoms and seek professional advice when needed.

Phenergan Interactions

When taking this medication, it’s important to be aware of potential interactions with other drugs or substances. This medication can interact with skin-applied antihistamines like diphenhydramine creams or sprays, and metoclopramide. Using it alongside other products that cause drowsiness or breathing issues, such as opioid painkillers (e.g., codeine, hydrocodone), alcohol, cannabis, sleep or anxiety medications (e.g., alprazolam, lorazepam, zolpidem), and muscle relaxants (e.g., carisoprodol, cyclobenzaprine), can increase the risk of severe side effects, including significant drowsiness or breathing difficulties. It’s crucial to inform your healthcare provider if you are using any of these substances.

Additionally, be cautious with other medications such as Bepridil, Bromopride, Calcium Oxybate, and others listed, as combining these with this medication is generally not recommended. If your doctor prescribes both, they may adjust dosages or usage frequency to mitigate risks.

Also, be aware that this medication can interfere with certain lab tests, potentially leading to false results. Make sure to inform lab staff and all your healthcare providers that you are using this drug.

Always consult with your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, vitamins, and supplements, to ensure safe usage and avoid interactions.

Phenergan FAQs
What is Phenergan mainly used for?

Phenergan is mainly used for its antihistamine properties to treat allergy symptoms such as itching, runny nose, and sneezing. It is also used to prevent motion sickness, treat nausea and vomiting, and as a sedative or sleep aid.

Phenergan, which contains promethazine, is considered a sedating antihistamine. It has sedative properties and can cause drowsiness, but it is not classified as a strong sedative like some other medications specifically used for sedation. It is often used to help with sleep or to manage nausea and motion sickness, partly due to its sedative effects.

Phenergan is commonly prescribed for the treatment of allergy symptoms, such as itching, runny nose, and sneezing. It is also used to prevent motion sickness, treat nausea and vomiting, and as a sedative or sleep aid. Additionally, it may be used to enhance the effects of certain pain medications.

Promethazine is most commonly used to treat allergy symptoms, such as itching, runny nose, and sneezing. It is also frequently used to prevent motion sickness, treat nausea and vomiting, and as a sedative or sleep aid.

The choice between Zofran (ondansetron) and Phenergan (promethazine) depends on the specific medical situation and the patient's needs. Zofran is often preferred for preventing nausea and vomiting associated with chemotherapy, radiation therapy, or surgery due to its effectiveness and lower sedative effects. Phenergan, on the other hand, is sometimes used for nausea and vomiting, but it has more sedative properties and can be used for motion sickness or as a sedative. A healthcare provider should be consulted to determine the most appropriate medication based on the individual's condition and medical history.