Disulfiram

Drug Details

Disulfiram is a medication used to help treat alcohol use disorder in adults. It is most effective when used in combination with counseling and support groups. This medication functions as an alcohol antagonist, which means it interferes with the liver's ability to break down alcohol. Specifically, disulfiram blocks a protein in the liver, resulting in slower alcohol metabolism. This leads to unpleasant reactions if alcohol is consumed while taking the medication, reinforcing abstinence from alcohol. Disulfiram is taken orally once a day, and while the brand name Antabuse is no longer available, generic versions are still accessible. Some people may experience side effects such as drowsiness and headache. It is important to consult with a healthcare provider before starting disulfiram to ensure it is a safe and appropriate treatment option.