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This medication should not be given to a patient without their knowledge. Do not take this medication if you are under the influence of alcohol or have drunk alcohol in the last 12 hours.

Drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Tell your doctor right away if you have any serious side effects, including: decreased sexual ability, vision changes, numbness/tingling of arms/legs, muscle weakness, mental/mood changes (such as agitation, confusion, extreme excitement), seizures. This drug may rarely cause serious (rarely fatal) liver disease. If you notice any of the following serious side effects, tell your doctor right away: nausea/vomiting that doesn't stop, severe stomach/abdominal pain, dark urine, yellowing eyes/skin. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Some products that may interact with this drug are: alcohol-containing products (such as cough and cold syrups, aftershave), amitriptyline, benznidazole, "blood thinners" (such as warfarin), certain medications for seizures (including hydantoins such as phenytoin/fosphenytoin), fezolinetant, isoniazid, metronidazole, theophylline, tinidazole. This medication can increase the side effects of caffeine. Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas) or eating large amounts of chocolate. This medication may interfere with certain lab tests (such as urine VMA/HVA tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.