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This medication comes with several important safety warnings and contraindications that should be reviewed carefully. It is crucial to consult your healthcare provider if you have any concerns or questions regarding these warnings.

• Cancer Risk: Prolonged use of tinidazole (Tindamax) has shown an increased risk of tumors in animal studies. It is unclear if short-term use carries the same risk. Do not exceed the prescribed duration or frequency without consulting your primary care provider.

• Neurological Effects: In rare cases, tinidazole (Tindamax) may cause severe brain and nerve issues, including seizures. Seek immediate medical attention if you experience convulsions, speech difficulties, coordination problems, confusion, headaches, nausea, or vomiting, as these could indicate brain damage.

• Fungal Infections: Use of tinidazole (Tindamax) may increase the likelihood of developing fungal infections, such as vaginal yeast infections. Report any persistent or worsening symptoms to your care team, who may prescribe antifungal treatment if necessary.

• Blood Cell Count: Some individuals may experience a decrease in blood cell count, particularly those with a history of blood disorders or those taking medications that affect white blood cell counts. Notify your healthcare team if you experience symptoms like fatigue, weakness, unusual bleeding, bruising, or fever. Regular lab work may be required to ensure safe use.

• Drug Resistance: Incorrect use of tinidazole (Tindamax), such as overuse or inappropriate dosing, can lead to drug-resistant infections. Adhere to the prescribed instructions to ensure the medication remains effective.

• Drug Interactions: Tinidazole (Tindamax) can alter the body's processing of other medications. Avoid combining it with disulfiram, as this may lead to delusions and hallucinations. Maintain a two-week interval between using these medications.

Contraindications: Do not use this medication if you have an allergy to nitroimidazole medications, such as metronidazole (Flagyl). Always discuss your medical history with your healthcare provider to avoid potential risks.

Common side effects:

• Metallic or bitter taste
• Nausea
• Decreased appetite
• Belly cramps
• Vomiting
• Constipation
• Dizziness
• Headaches

Less common but important to monitor:

• Trouble sleeping
• Drowsiness
• Muscle or joint pain
• Urine darkening
• Oral thrush or tongue discoloration
• Excessive gas
• Painful or trouble urinating
• Pelvic pain
• Heavy menstrual periods
• Upper respiratory infections (persistent coughing or sore throat)

Serious side effects:

• Unsteadiness
• Seizures
• Numbness and tingling in the limbs
• Severe allergic reaction (rash, swelling, difficulty breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Disulfiram

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Capecitabine
• Doxifluridine
• Fluorouracil
• Tegafur
• Lopinavir/ritonavir solution
• Lithium

Interactions with low risk that usually do not require a change in therapy:

• Products containing alcohol (e.g., cough and cold syrups, aftershave)
• Products containing propylene glycol