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This medication requires careful consideration of potential safety risks and warnings. Please review the following information and consult your healthcare provider if you have any questions or concerns:

• Reduced Blood Flow: This medication can occasionally cause a significant reduction in blood flow to the brain, arms, hands, feet, or other extremities, potentially leading to stroke or tissue damage. The risk increases when taken with certain drugs that elevate ergotamine levels in the body, such as HIV protease inhibitors, macrolide antibiotics (e.g., erythromycin, clarithromycin), mifepristone, certain antidepressants (e.g., nefazodone, fluoxetine), azole antifungals (e.g., ketoconazole), and others. It is crucial to inform your healthcare provider of all medications you are currently taking to avoid dangerous interactions. Seek immediate medical attention if you experience symptoms like pain, numbness, or coldness in your extremities or any signs of a stroke, such as weakness, slurred speech, or facial drooping.

• Fibrosis Risk: Though rare, prolonged or frequent use of this medication can lead to fibrosis (scarring) in the stomach, lungs, or heart. Use this medication only as needed, and if you find yourself requiring it daily, contact your healthcare provider to explore alternative treatments.

• Allergic Reactions: This medication contains yellow #5 dye (tartrazine), which may cause allergic reactions in some individuals, such as airway constriction or difficulty breathing. If you have a known allergy to tartrazine or similar yellow dyes, discuss this with your healthcare provider or pharmacist.

Contraindications: Do not use this medication if you have any of the following conditions without consulting your healthcare provider:

• Use of drugs that elevate ergotamine levels, like macrolide antibiotics and protease inhibitors.
• Pregnancy or potential to become pregnant.
• Peripheral vascular disease or other blood vessel issues in hands or feet.
• Heart disease, high blood pressure, liver or kidney disease.
• Sepsis (a severe infection-related complication).

In case of overdose, seek emergency medical assistance immediately. Always adhere to the prescribed dosage and consult with your healthcare provider for any concerns or if you experience adverse reactions.

Common side effects:

• nausea
• vomiting
• upset stomach
• restlessness
• trouble sleeping
• dizziness

Serious side effects:

• irregular heartbeat
• numbness or tingling in fingers and toes
• blue discoloration of fingers, toes, or nails
• cold hands or feet
• muscle pain or weakness
• severe stomach or abdominal pain
• unusual lower back pain
• changes in the amount of urine
• chest, jaw, or left arm pain
• confusion
• difficulty speaking
• vision changes
• weakness on one side of the body
• poor blood flow to the extremities causing pain, numbness, coldness, or a pale color in the hands or feet
• allergic reactions such as rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Triptan medications (such as sumatriptan, rizatriptan)