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Ertugliflozin may cause frequent urination, dizziness, or lightheadedness. To minimize dizziness, stand up slowly from sitting or lying down. While many people tolerate this drug well, it's important to be aware of serious side effects. Contact your doctor immediately if you experience symptoms of a urinary tract infection, such as burning or painful urination and pink or bloody urine, or if you notice changes in urine amount or swelling in the legs and feet, which may indicate kidney issues.

Seek immediate medical attention for very serious side effects like unusual tiredness, nausea, vomiting, stomach pain, or difficulty breathing. Ertugliflozin may also lead to yeast infections in the genital area or a rare but severe bacterial infection called Fournier's gangrene. Be vigilant for signs such as unusual discharge, itching, or swelling, and seek urgent care for pain, redness, or swelling around the genital area accompanied by fever.

There's an increased risk of lower limb amputation, particularly for individuals with poor blood circulation or previous amputations. Regularly check your feet for new pain or sores and notify your doctor. While ertugliflozin usually doesn't cause low blood sugar, it can occur if combined with other diabetes medications, insufficient food intake, or intense exercise. Symptoms include sweating, shaking, fast heartbeat, and dizziness. Carry glucose tablets or other quick sugar sources to manage low blood sugar.

High blood sugar, marked by increased thirst and urination, should also be reported to your doctor. This medication can lead to dehydration, potentially causing serious kidney damage. Ensure adequate fluid intake and watch for signs of dehydration such as decreased urination and dry mouth. Although rare, a serious allergic reaction may occur, requiring immediate medical help if you experience rash, swelling, severe dizziness, or trouble breathing. Always consult your doctor for any unexplained symptoms.