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When taking this medication, you might experience some mild side effects such as nausea, vomiting, headaches, bloating, or breast tenderness. There could also be swelling in your ankles or feet due to fluid retention, and some may notice changes in weight. It's common to have vaginal bleeding between periods, known as spotting, or to miss or have irregular periods, especially during the initial months of use. These side effects are typically mild, but if they persist or worsen, it's important to consult with a healthcare professional.

Monitoring your blood pressure is advisable, as this medication can increase it. Should you notice consistently high readings, seek medical advice. More serious side effects, although less common, require immediate attention. These include lumps in the breast, significant mood changes, severe abdominal pain, or unusual changes in vaginal bleeding patterns. Additionally, dark urine or yellowing of the eyes and skin are signs that should prompt a medical consultation.

There is a rare risk of serious blood clot-related issues, such as heart attacks or strokes. Be alert to symptoms like chest pain, sudden dizziness, severe headaches, or trouble speaking, and seek emergency help if they occur. Allergic reactions are also rare but serious, with symptoms like rash, swelling, and breathing difficulties warranting urgent medical attention.

This overview does not cover all possible side effects. If you observe any other unusual symptoms, reach out to a healthcare provider for guidance.

Certain medications can interact with this drug, including aromatase inhibitors (like Anastrozole and Exemestane), fezolinetant, ospemifene, Tamoxifen, Tizanidine, and Tranexamic Acid. Additionally, some combination treatments for chronic hepatitis C (such as ombitasvir/paritaprevir/Ritonavir, with or without dasabuvir) may also interact.

Some medicines can reduce the effectiveness of hormonal birth control by lowering the hormone levels in your body, which may lead to pregnancy. These include drugs like griseofulvin, Modafinil, rifamycins (such as Rifampin and Rifabutin), ritonavir, St. John's wort, medications for seizures (such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, and Topiramate), and certain HIV medications (like nelfinavir and Nevirapine).

Inform your doctor when you begin taking any new medication and discuss the need for additional reliable birth control methods. Alert your doctor if you notice any unusual spotting or breakthrough bleeding, as these could indicate that your birth control is not functioning effectively.

This medication may also affect certain laboratory tests, such as those for blood clotting factors or thyroid function, potentially leading to inaccurate results. Ensure that lab personnel and all of your healthcare providers are aware of your medication use.