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It is essential to be aware of the safety information related to the use of Lantus (insulin glargine) to ensure your health and well-being. If you have any questions or concerns, please discuss them with your healthcare provider.

• Risk of Infections: Sharing Lantus pens, syringes, or needles can expose you and others to severe infections, such as HIV and hepatitis B. Always use your own supplies.

• Blood Sugar Levels: Alterations in your insulin regimen, including changes in the injection site or switching to a Lantus biosimilar, may influence your blood sugar. Additionally, frequent injections into areas with lipodystrophy can result in high blood sugar.

• Hypoglycemia (Low Blood Sugar): Using Lantus alone or with other diabetes medications can cause dangerously low blood sugar. Contributing factors include changes in diet or exercise, alcohol consumption, and liver or kidney issues. Follow your prescription instructions closely to avoid this risk.

• Low Potassium Levels: Lantus can lower blood potassium levels, especially if combined with certain medications like loop diuretics. Regular blood tests may be required to monitor your potassium levels. Seek medical attention if you experience symptoms like weakness, muscle cramps, or constipation.

• Fluid Retention and Heart Failure: Using Lantus with glitazones, such as Actos, might lead to fluid retention, worsening heart failure symptoms like difficulty breathing and swelling. If you have heart failure, this combination could be particularly hazardous.

• Severe Allergic Reactions: Although rare, Lantus can trigger severe allergic reactions, including anaphylaxis. Immediate medical attention is necessary if you notice swelling in the lips, face, or tongue, rash, or difficulty breathing.

Contraindications:

• Hypoglycemia: Do not use Lantus if you currently have low blood sugar, as it could exacerbate the condition. Consult with your healthcare provider for guidance.

When taking this medication, some common side effects may include upper respiratory tract infections, which can affect up to 29% of users, as well as swelling in the hands or feet and high blood pressure, both seen in about 20% of patients. Other mild side effects include flu-like symptoms, sinus infections, or bronchitis (up to 19%), cataracts (15%), joint pain (14%), pain in the hands and feet (13%), back pain (13%), cough (12%), urinary tract infections (11%), diarrhea (11%), depression (11%), and headaches (10%). These symptoms are usually mild, but if they persist or worsen, consult your healthcare provider for guidance.

More severe side effects require immediate medical attention. These include dangerously low blood sugar levels (hypoglycemia), which can manifest as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling in the hands and feet. Low potassium levels may present as muscle cramps, weakness, irregular heartbeat, or constipation. If you experience any of these symptoms, it's important to seek medical care promptly.

Additionally, severe allergic reactions, though rare, can occur. Symptoms such as rash, itching or swelling particularly of the face, tongue, or throat, severe dizziness, or trouble breathing should be treated as medical emergencies. Always inform your healthcare provider of any side effects you experience, even if they are not listed here, to ensure safe and effective use of your medication.

When taking Lantus (insulin glargine), it's important to be aware of potential interactions with other medications. Inform your doctor and pharmacist about all other medicines or supplements you are using, including prescription drugs, over-the-counter products, vitamins, and herbal supplements. Be aware that the following interactions may occur:

Beta-blockers, such as metoprolol and Propranolol, including eye drops like Timolol for glaucoma, can mask the rapid heartbeat that usually signals low blood sugar (hypoglycemia). However, they do not affect other low blood sugar symptoms, such as dizziness, hunger, or sweating. If you use these medications, it's vital to monitor your blood sugar levels regularly and report any symptoms of high or low blood sugar to your doctor. Adjustments to your diabetes medication, exercise routine, or diet may be necessary.

Additionally, Lantus may interact with a wide range of medications, including antibiotics like Ciprofloxacin and heart medications such as metoprolol, among others. These interactions might either require careful monitoring or dosage adjustments. Your doctor may need to modify how often you use these medications or their doses to ensure your safety and the effectiveness of your treatment. Always discuss any changes in medication with your healthcare provider to maintain optimal blood sugar control.