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Here is an important overview of safety information regarding the use of latanoprost (Xalatan), a prostaglandin eye drop. Please take note of the potential risks and guidelines for safe use, and consult your healthcare provider if you have any concerns.

• Changes in Eye Appearance: Latanoprost can lead to darkening of the eye color, eyelids, and eyelashes. This change is usually noticeable after prolonged use and may become permanent. While these changes are generally not harmful, regular check-ups with your healthcare provider are recommended to ensure ongoing eye health.

• Eyelash Alterations: The medication may cause eyelashes to grow longer and thicker. These effects typically subside after discontinuing use.

• Eye Inflammation and Swelling: Latanoprost may cause or worsen eye inflammation or swelling of the macula (macular edema), especially in individuals with pre-existing eye inflammation or lens damage. If you experience any eye discomfort or vision changes, contact your healthcare provider immediately.

• Herpes Eye Infections: Those with a history of herpetic keratitis should be cautious, as latanoprost may trigger a recurrence of these infections. Avoid using the medication if you currently have a herpes eye infection.

• Bacterial Infections: There is a risk of bacterial keratitis if the eye drop bottle becomes contaminated. To prevent this, wash your hands before use and avoid contact between the dropper tip and any surfaces, including your eye and hands.

• Contact Lens Precautions: Latanoprost contains benzalkonium chloride, which can be absorbed by soft contact lenses and potentially cause harm. Remove contact lenses before administering the drops and wait at least 15 minutes before reinserting them.

Please follow these precautions to ensure safe use of latanoprost (Xalatan) and protect your eye health.

Common side effects:

• blurred vision
• temporary stinging after application
• itching of the eyes
• redness of the eyes
• feeling as if something is in your eye
• changes in eyelashes' number, color, length, or thickness
• eyelid changes such as skin darkening
• dry eyes
• eyelid crusting
• discomfort
• increased sensitivity to light

Less common but important to monitor:

• brown discoloration in the iris
• more tears than usual
• eyelid discomfort or redness
• light sensitivity

Serious side effects:

• eye pain
• suspected eye infections
• rapid vision changes
• allergic reaction characterized by rash, severe itching, swelling, dizziness, or trouble breathing

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• topically applied Bimatoprost