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This medication carries important safety information that should be carefully reviewed. It is crucial to be aware of the potential risks, precautions, and necessary actions in case of an emergency. Consult your healthcare provider with any concerns or questions.

• Risk of Dehydration in Young Children: This medication should not be used in children under 2 years old due to the risk of severe dehydration, which can be life-threatening. Animal studies have shown severe and fatal dehydration in infants. Although older children are at lower risk, there is insufficient data on younger infants. Always store the medication out of the reach of children. In case of accidental ingestion by a child, seek immediate medical assistance by contacting emergency services or the poison control center at 1-800-222-1222.

• Severe Diarrhea: Linzess (linaclotide) can occasionally cause severe diarrhea, potentially leading to dehydration that may require hospitalization. It is important to maintain adequate fluid intake while on this medication. Discontinue use and seek medical attention promptly if you experience sudden abdominal pain, severe diarrhea, red or black tarry stools, dizziness, or fainting, as these symptoms may indicate severe dehydration.

• Contraindications: Do not use this medication if you are a child under the age of 2 or if you have a known or suspected bowel obstruction. Consult your healthcare provider if you experience any of these conditions before using the medication.

Always adhere to medical advice and consult your healthcare provider for personalized guidance based on your specific health needs.

When taking this medication, some individuals may experience mild side effects such as diarrhea, stomach pain, gas, or bloating. These are generally not serious, but if they persist or worsen, it is advisable to consult a healthcare provider. Additionally, some users have reported headaches, nausea, vomiting, indigestion, or a feeling of needing an urgent bowel movement. In some cases, there might be difficulty in controlling bowel movements or infections like upper respiratory tract infections, sinus infections, or stomach flu.

Serious side effects, although rare, demand immediate medical attention. These include severe diarrhea, bloody or tar-like black stools, and symptoms of dehydration such as confusion, dizziness, fainting, or a rapid heartbeat. It is crucial to be vigilant about these symptoms and seek urgent care if they occur.

Lastly, allergic reactions to this medication are rare but serious. If you notice symptoms such as a rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek emergency medical help. Always communicate with your healthcare provider about any unusual effects you experience.