Nitrofurantoin Macrocrystal

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nitrofurantoin macrocrystal

Nitrofurantoin, also known as Macrobid, is an antibiotic prescribed for the treatment and prevention of urinary tract infections (UTIs). It works by accumulating in the urine and targeting bacteria in the urinary tract, interfering with the proteins they require for survival. This medication is not effective against viral infections, like the common cold or flu, and unnecessary use can reduce its effectiveness over time. Patients may experience side effects such as nausea, headache, gas, or changes in urine color to dark yellow or brown. Nitrofurantoin should not be administered to children under one month old due to the risk of a blood condition known as hemolytic anemia. There is a generic version available that may be more affordable, and Nitrofurantoin generally has few interactions with other medications. Always consult your healthcare provider to ensure this medication is safe and suitable for your condition.
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100MG, Nitrofurantoin Macrocrystal (30 Capsules)

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$20.70

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Macrodantin dosage forms

The average cost for 30 Capsules of Macrodantin (nitrofurantoin macrocrystal) at 100MG is $11.46 with a free coupon. This is 16.98% off the average retail price of $67.5
DosageQuantityPrice fromPer unit
100MG30 Capsules$11.46$0.38
25MG30 Capsules$32.46$1.08
50MG30 Capsules$8.82$0.29

Macrodantin Warnings

This document outlines essential safety and warning information for the use of nitrofurantoin (Macrobid). It is crucial to review these details and discuss any concerns with your healthcare provider.

  • Lung Damage: Rarely, prolonged use of nitrofurantoin, especially beyond six months, may cause lung damage. If you experience persistent coughing or difficulty breathing, seek medical attention promptly.

  • Liver Damage: In very rare cases, nitrofurantoin can lead to severe liver damage, particularly in individuals with existing or previous liver issues. Watch for symptoms such as unexplained abdominal pain, nausea, vomiting, dark urine, light-colored stools, or yellowing of the skin or eyes. Immediate consultation with your healthcare provider and liver function testing may be necessary.

  • Nerve Damage (Neuropathy): Although uncommon, nitrofurantoin can cause nerve damage, especially in those with kidney issues. Symptoms may include numbness, tingling, or prickling sensations. Long-term users may require regular blood tests to monitor for potential nerve damage.

  • Breakdown of Red Blood Cells (Hemolytic Anemia): This medication can affect red blood cells, particularly in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Those of Black, Mediterranean, or Middle Eastern descent are at higher risk. Report any unexplained weakness, dizziness, or fatigue to your healthcare provider.

  • Severe Diarrhea: As with other antibiotics, nitrofurantoin may cause diarrhea, sometimes due to an overgrowth of Clostridioides difficile (C. diff). If you experience watery or bloody stools, stomach cramps, or fever, contact your provider immediately. Maintain good hygiene to prevent spreading infection.

Contraindications: Avoid using nitrofurantoin if you have a history of liver damage or jaundice linked to its use, severe kidney issues, reduced or absent urination, are a female in the late stages of pregnancy or in labor, or if the patient is a child under one month old. Always consult with your healthcare provider if any of these conditions apply.

Macrodantin Side Effects

When taking this medication, some people may experience common side effects such as nausea, headache, and gas. While these are typically mild and often resolve on their own, taking the medication with food can help alleviate nausea. If these symptoms persist or worsen, it's important to consult your healthcare provider.

In some cases, other side effects may occur, including diarrhea, vomiting, upset stomach, stomach pain, dizziness, drowsiness, itchiness, fever, chills, and a "pins and needles" sensation in the arms and legs. These effects are generally not serious, but if they become bothersome, reaching out to a healthcare professional is advised.

Rarely, this medication can cause serious side effects that require immediate medical attention. These include severe allergic reactions, characterized by hives, rash, muscle aches, chills, fever, swelling of the lips or tongue, and difficulty breathing. Severe diarrhea and trouble breathing or a new/worsening cough are also critical signs to watch for.

Additionally, this medication can lead to liver problems, which are identified by symptoms such as stomach bloating, severe stomach pain with vomiting, yellowing of the skin or eyes, and dark urine. Prompt medical evaluation is crucial if any of these signs appear.

In rare instances, prolonged use may cause oral thrush or vaginal yeast infections, indicated by white patches in the mouth or changes in vaginal discharge. Uncommon yet serious side effects include lung issues, severe headaches, signs of infection, easy bruising, mental changes, vision issues, and nerve or blood problems. If any unusual symptoms arise, seek medical guidance immediately.

Most people using this medication do not experience serious side effects. However, being aware of these possibilities helps ensure prompt action if needed. Always discuss any concerns or symptoms with your healthcare provider.

Macrodantin Interactions

Nitrofurantoin, also known as Macrobid, can interact with certain medications and supplements. It is crucial to inform your doctor and pharmacist about all the medications and supplements you are taking, whether they are prescribed, over-the-counter, vitamins, or herbal products. Some interactions may not be listed here, so complete transparency with your healthcare providers is essential.

Particularly, Nitrofurantoin may interfere with lab tests, such as urine glucose tests, potentially leading to incorrect results. It's important that all your doctors and lab technicians are aware that you are using this medication.

Additionally, there are specific medications with which Nitrofurantoin is generally not recommended unless absolutely necessary. If Nitrofurantoin and these medications, such as Cholera Vaccine, Live, and Fluconazole, must be used together, your doctor may need to adjust the dosage or frequency of one or both medications to ensure safety and effectiveness.

Macrodantin FAQs
What is Macrodantin antibiotic used for?

Macrodantin is an antibiotic used to treat and prevent urinary tract infections (UTIs). It works by stopping the growth of bacteria in the urinary tract.

Macrodantin and Bactrim are not the same. Macrodantin contains the active ingredient nitrofurantoin, while Bactrim is a combination of sulfamethoxazole and trimethoprim. They are both antibiotics but are used to treat different types of bacterial infections.

For urinary tract infections (UTIs), the choice of antibiotic depends on the specific bacteria causing the infection and its resistance pattern. While Macrobid (nitrofurantoin) is commonly used for uncomplicated UTIs, other antibiotics that may be considered stronger or more appropriate in certain cases include:- Ciprofloxacin or levofloxacin, which are fluoroquinolones.- Trimethoprim-sulfamethoxazole (Bactrim or Septra), if the bacteria are susceptible.- Amoxicillin-clavulanate (Augmentin) or cephalosporins for broader coverage.It is important for a healthcare provider to determine the most appropriate antibiotic based on the patient's medical history, local resistance patterns, and the severity of the infection.

Macrodantin, which contains the active ingredient nitrofurantoin, can cause several side effects. Common side effects include nausea, headache, and loss of appetite. Some individuals may experience diarrhea, dizziness, or drowsiness. More serious side effects, though less common, can include lung problems, liver issues, or allergic reactions. If any severe side effects occur, it is important to seek medical attention promptly.

While taking Macrobid (nitrofurantoin), there are no specific foods that need to be avoided. However, it is generally recommended to take Macrobid with food or milk to enhance absorption and reduce the risk of stomach upset. It is important to follow the healthcare provider's instructions and maintain a balanced diet while on this medication. If there are any concerns or unusual symptoms, consulting with a healthcare professional is advised.