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The safety and warning information below provides essential guidance on the proper use of erythromycin eye ointment. It is crucial to adhere to these instructions to minimize potential risks and ensure safe application. If you have any questions or concerns, please consult your healthcare provider.

• Application Area: Erythromycin eye ointment is intended exclusively for application on the eye's surface. Avoid using it in your mouth, nose, or any other body parts.

• Risk of Infections: Prolonged use of erythromycin eye ointment can increase the likelihood of developing other eye infections, such as fungal infections. It is not suitable for treating viral eye infections, as it may exacerbate the condition. Contact your healthcare provider if you experience symptoms like eye pain, redness, blurred vision, sensitivity to light, or watery discharge, or if there is no improvement in your condition within a few days, as these could indicate a new or worsening infection.

• Allergic Reactions: If you have a history of allergies to antibiotics, such as clarithromycin or azithromycin, inform your healthcare provider before using erythromycin eye ointment. Be vigilant for signs of an allergic reaction, including swollen eyelids or red, itchy eyes. If these symptoms occur, discontinue use immediately and contact your healthcare provider.

There are no specific contraindications available for erythromycin eye ointment. Always follow the prescribed duration of use and dosage to avoid complications.

Common side effects:

• nausea
• vomiting
• diarrhea
• stomach pain or cramping
• loss of appetite
• mild eye irritations
• redness

Less common but important to monitor:

• oral thrush
• yeast infections
• white patches in the mouth
• changes in vaginal discharge

Serious side effects:

• signs of liver disease
• persistent nausea or vomiting
• yellowing of the eyes or skin
• dark urine
• severe stomach pain
• unusual tiredness
• muscle weakness
• trouble speaking
• blurred vision
• drooping eyelids
• hearing loss
• severe dizziness
• fainting
• fast or irregular heartbeat
• serious intestinal condition (C. difficile)
• persistent diarrhea
• abdominal pain
• blood or mucus in the stool
• severe allergic reaction
• rash
• swelling of the face, tongue, or throat
• difficulty breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Amiodarone
• Dofetilide
• Pimozide
• Procainamide
• Propafenone
• Quinidine
• Sotalol
• Digoxin

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Itraconazole
• Ketoconazole
• Diltiazem
• Verapamil
• Carbamazepine
• Phenytoin
• Bromocriptine
• Colchicine
• Midazolam
• Triazolam
• Eletriptan
• Ergotamine
• Dihydroergotamine
• Sildenafil
• Tadalafil
• Lovastatin
• Simvastatin
• Vinblastine
• Clindamycin
• Warfarin