Methotrexate Sodium (pf) coupons
Methotrexate Sodium (pf)

Methotrexate Sodium (pf) Coupons & Savings Card – Discount Prices from $3.68

Methotrexate is prescribed for the treatment of specific cancers, severe psoriasis, and rheumatoid arthritis. It is also used for polyarticular juvenile idiopathic arthritis (pJIA) in children. As an antimetabolite, methotrexate functions by inhibiting the growth of cancer cells and preventing the immune system from damaging healthy tissues. In rheumatoid arthritis, early intervention with methotrexate can help minimize joint damage and maintain joint functionality.
Our coupons are free to use. Before paying, show the pharmacist your Methotrexate Sodium (pf) savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Methotrexate Sodium (pf) prices will update based on your prescription needs. Above our Methotrexate Sodium (pf) coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Methotrexate Sodium (pf) at the lowest price with our prescription discount card.
Methotrexate Sodium (pf) WarningsMethotrexate Sodium (pf) Side EffectsMethotrexate Sodium (pf) InteractionsFAQs

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10ML of 250MG/10ML, Methotrexate Sodium (pf) (1 Vial)

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CVS

$26.06

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$3.68

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$8.83

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$17.69

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$43.10

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Methotrexate Sodium (pf) savings card

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Methotrexate Sodium (pf) dosage forms

The average cost for 1 Vial of Methotrexate Sodium (pf) at 2ML of 50MG/2ML is $15.72 with a free coupon. This is 89% off the average retail price of $45.29
DosageQuantityPrice fromPer unit
2ML of 50MG/2ML1 Vial$5.2$5.2
10ML of 250MG/10ML1 Vial$3.68$3.68
40ML of 1GM/40ML1 Vial$26.93$26.93
40ML of 1000MG/40ML1 Vial$1.01$1.01

Methotrexate Sodium (pf) Warnings

Methotrexate has rarely caused serious (sometimes fatal) side effects. This medication should be used only to treat cancer or severe diseases caused by an overactive immune system (such as psoriasis, rheumatoid arthritis). Methotrexate formulations with preservatives must not be used for high-dose treatment or injected into the area around the spinal cord (intrathecal). Methotrexate has caused birth defects and death in unborn babies. Women must avoid becoming pregnant while using this medication. Pregnant women who have psoriasis or rheumatoid arthritis must not use methotrexate. () If you have kidney problems or excess body water (ascites, pleural effusion), you must be closely monitored and your dose may be adjusted or stopped by your doctor. Methotrexate (usually at high dosages) has rarely caused severe (sometimes fatal) blood/bone marrow problems (decreasing your body's ability to fight infections) and stomach/intestinal disease (such as bleeding) when used at the same time as non-steroidal anti-inflammatory drugs (NSAIDs such as indomethacin, ketoprofen). NSAIDs should not be used with high-dose methotrexate. Caution is advised if you also take aspirin. NSAIDs/aspirin may be used with low-dose methotrexate such as for the treatment of rheumatoid arthritis if directed by your doctor. If your doctor has told you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should keep taking the aspirin unless your doctor tells you not to. Ask your doctor or pharmacist for more details on the safe use of these drugs (such as close monitoring by your doctor, keeping the same doses of NSAIDs). In rare instances, this drug may also cause liver problems when it is used for long periods of time. If you are using methotrexate long term, a liver biopsy is usually recommended. Methotrexate use has rarely caused serious (sometimes fatal) side effects, such as lung problems, lung infections (Pneumocystis jiroveci pneumonia), skin reactions, diarrhea, and mouth sores (ulcerative stomatitis). () Lumps (tumors/abnormal growths) may very rarely appear during methotrexate use. The drug must be stopped and treatment may be needed. Tell your doctor right away if new lumps/growths occur. When used to treat tumors, methotrexate sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, drink plenty of fluids unless your doctor directs you otherwise. Also, your doctor may prescribe an additional medication. Tell your doctor right away if you have symptoms such as irregular heartbeat, low back/side pain, signs of kidney problems (such as pink/bloody urine, change in the amount of urine, painful urination), or muscle spasms/weakness. When this medication is used with radiation treatment, it may rarely increase the risk of tissue and bone damage. Discuss the risks and benefits of your treatment with your doctor.

Methotrexate Sodium (pf) Side Effects

Common side effects:

  • Headache
  • Dizziness
  • Nausea

Less common but important to monitor:

  • Persistent cough
  • Unexplained weight loss

Serious side effects:

  • Chest pain
  • Severe allergic reaction

Methotrexate Sodium (pf) Interactions

Some products that may interact with this drug include: acitretin, asparaginase, leflunomide, other drugs that can cause kidney problems (such as cisplatin), other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, probenecid, procarbazine, pyrimethamine, sulfa medications, tetracyclines. Certain drugs that reduce stomach acid (proton pump inhibitors-PPIs such as esomeprazole, omeprazole, pantoprazole) may increase the amount of methotrexate in your blood. This effect may increase the risk of side effects, especially with high-dose methotrexate treatment. Ask your doctor or pharmacist for details and ways to lessen the risk of side effects.
Methotrexate Sodium (pf) FAQs
What is methotrexate sodium used for?

Methotrexate sodium is used to treat certain types of cancer, such as breast cancer, lung cancer, and leukemia. It is also used to manage severe psoriasis and rheumatoid arthritis when other treatments have not been effective. Methotrexate works by slowing or stopping the growth of cancer cells and suppressing the immune system to reduce inflammation.

Sodium bicarbonate is given with methotrexate to alkalinize the urine. This helps to prevent the crystallization of methotrexate and its metabolites in the renal tubules, thereby reducing the risk of nephrotoxicity. Alkalinization enhances the solubility of methotrexate, facilitating its excretion and minimizing potential kidney damage.

After taking methotrexate, it is recommended to flush the toilet twice to ensure that any residual medication in the urine is thoroughly removed. This precaution helps minimize the risk of exposure to others, as methotrexate can be harmful if it comes into contact with skin or is ingested.

Methotrexate can affect the full blood count by causing bone marrow suppression, which may lead to a decrease in the number of blood cells. This can result in conditions such as leukopenia (low white blood cell count), anemia (low red blood cell count), and thrombocytopenia (low platelet count). Regular monitoring of the full blood count is recommended for patients taking methotrexate to detect and manage these potential side effects.

When taking methotrexate, it is advisable to avoid foods that are high in folic acid, as methotrexate can interfere with folic acid metabolism. Foods rich in folic acid include leafy green vegetables, fortified cereals, and certain legumes. Additionally, alcohol consumption should be limited or avoided, as it can increase the risk of liver damage when combined with methotrexate. It is important to follow any specific dietary recommendations provided by a healthcare provider.

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