Methotrexate Sodium (pf) coupons
Methotrexate Sodium (pf)

Methotrexate Sodium (pf) Coupons & Discount Card - Compare Prices Near You

Methotrexate is prescribed for treating specific cancers, severe psoriasis, and rheumatoid arthritis. It is also effective for managing polyarticular juvenile idiopathic arthritis (pJIA) in children. As an antimetabolite, methotrexate functions by hindering the growth of cancer cells and preventing the immune system from damaging healthy tissues. Starting methotrexate early in rheumatoid arthritis treatment can help minimize joint damage and maintain joint function.
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Methotrexate Sodium (pf) WarningsMethotrexate Sodium (pf) Side EffectsInteractionsFAQs

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10ML of 250MG/10ML, Methotrexate Sodium (pf) (1 Vial)

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CVS

$26.20

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$2.00

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$3.68

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$8.83

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$43.10

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Methotrexate Sodium (pf) savings card

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Methotrexate Sodium (pf) dosage forms

The average cost for 1 Vial of Methotrexate Sodium (pf) at 2ML of 50MG/2ML is $2 with a free coupon. This is 7.30% off the average retail price of $27.39
DosageQuantityPrice fromPer unit
2ML of 50MG/2ML1 Vial$2$2
10ML of 250MG/10ML1 Vial$2$2
40ML of 1GM/40ML1 Vial$8.37$8.37
40ML of 1000MG/40ML1 Vial$19.14$19.14

Methotrexate Sodium (pf) Warnings

Methotrexate has rarely caused serious (sometimes fatal) side effects. This medication should be used only to treat cancer or severe diseases caused by an overactive immune system (such as psoriasis, rheumatoid arthritis). Methotrexate formulations with preservatives must not be used for high-dose treatment or injected into the area around the spinal cord (intrathecal). Methotrexate has caused birth defects and death in unborn babies. Women must avoid becoming pregnant while using this medication. Pregnant women who have psoriasis or rheumatoid arthritis must not use methotrexate. (See also Precautions section.) If you have kidney problems or excess body water (ascites, pleural effusion), you must be closely monitored and your dose may be adjusted or stopped by your doctor. Methotrexate (usually at high dosages) has rarely caused severe (sometimes fatal) blood/bone marrow problems (decreasing your body's ability to fight infections) and stomach/intestinal disease (such as bleeding) when used at the same time as non-steroidal anti-inflammatory drugs (NSAIDs such as indomethacin, ketoprofen). NSAIDs should not be used with high-dose methotrexate. Caution is advised if you also take aspirin. NSAIDs/aspirin may be used with low-dose methotrexate such as for the treatment of rheumatoid arthritis if directed by your doctor. If your doctor has told you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should keep taking the aspirin unless your doctor tells you not to. Ask your doctor or pharmacist for more details on the safe use of these drugs (such as close monitoring by your doctor, keeping the same doses of NSAIDs). In rare instances, this drug may also cause liver problems when it is used for long periods of time. If you are using methotrexate long term, a liver biopsy is usually recommended. Methotrexate use has rarely caused serious (sometimes fatal) side effects, such as lung problems, lung infections (Pneumocystis jiroveci pneumonia), skin reactions, diarrhea, and mouth sores (ulcerative stomatitis). () Lumps (tumors/abnormal growths) may very rarely appear during methotrexate use. The drug must be stopped and treatment may be needed. Tell your doctor right away if new lumps/growths occur. When used to treat tumors, methotrexate sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, drink plenty of fluids unless your doctor directs you otherwise. Also, your doctor may prescribe an additional medication. Tell your doctor right away if you have symptoms such as irregular heartbeat, low back/side pain, signs of kidney problems (such as pink/bloody urine, change in the amount of urine, painful urination), or muscle spasms/weakness. When this medication is used with radiation treatment, it may rarely increase the risk of tissue and bone damage. Discuss the risks and benefits of your treatment with your doctor.

Methotrexate Sodium (pf) Side Effects

You might experience mild side effects such as nausea, vomiting, stomach pain, drowsiness, or dizziness. These symptoms are generally manageable, but if they persist or worsen, it’s important to consult with your healthcare provider. Temporary hair loss is also a possibility, but rest assured that normal hair growth typically resumes once treatment concludes.

While many individuals do not experience serious side effects, it's crucial to be aware of them. Notify your healthcare provider immediately if you develop mouth sores, diarrhea, signs of anemia like unusual tiredness or pale skin, or symptoms indicating liver issues such as persistent nausea, dark urine, abdominal pain, or yellowing of the skin or eyes. Other serious side effects to watch for include easy bruising or bleeding, black stools, swollen glands, bone pain, unusual skin changes, signs of kidney problems like changes in urination, dry cough, or muscle weakness.

Seek urgent medical attention if you encounter very serious side effects such as an irregular heartbeat, vision changes, one-sided weakness, a severe headache, neck stiffness, mood alterations, or seizures. This medication may also reduce your ability to fight infections, increasing the risk of severe infections. Promptly report any signs of infection, such as a persistent sore throat, fever, chills, or cough.

Allergic reactions to this medication are rare but can be serious. If you notice symptoms like a rash, itching, swelling, severe dizziness, or difficulty breathing, seek medical help immediately. This summary does not cover all potential side effects, so if you notice any unusual changes, reach out to your healthcare provider for further advice.

Interactions

Some medications can interact with this drug, including Acitretin, asparaginase, Leflunomide, and others that may affect the kidneys like Cisplatin. Drugs that can impact liver function such as Azathioprine, Sulfasalazine, and retinoids like Isotretinoin are also on the list, along with penicillins, Phenytoin, Probenecid, procarbazine, Pyrimethamine, sulfa drugs, and tetracyclines. Additionally, medications that lower stomach acid, specifically proton pump inhibitors like esomeprazole, Omeprazole, and Pantoprazole, can raise methotrexate levels in the blood. This increase can heighten the risk of side effects, especially during high-dose methotrexate therapy. Consult your doctor or pharmacist for more information and strategies to minimize these risks.
Methotrexate Sodium (pf) FAQs
Why give sodium bicarbonate with methotrexate?

Sodium bicarbonate is given with methotrexate to alkalinize the urine. This helps to prevent the crystallization of methotrexate and its metabolites in the renal tubules, thereby reducing the risk of nephrotoxicity. Alkalinization enhances the solubility of methotrexate, facilitating its excretion and minimizing potential kidney damage.

Methotrexate can affect the full blood count by causing bone marrow suppression, which may lead to a decrease in the number of blood cells. This can result in conditions such as leukopenia (low white blood cell count), anemia (low red blood cell count), and thrombocytopenia (low platelet count). Regular monitoring of the full blood count is recommended for patients taking methotrexate to detect and manage these potential side effects.

When taking methotrexate, it is advisable to avoid foods that are high in folic acid, as methotrexate can interfere with folic acid metabolism. Foods rich in folic acid include leafy green vegetables, fortified cereals, and certain legumes. Additionally, alcohol consumption should be limited or avoided, as it can increase the risk of liver damage when combined with methotrexate. It is important to follow any specific dietary recommendations provided by a healthcare provider.

Methotrexate sodium is used to treat certain types of cancer, such as breast cancer, lung cancer, and leukemia. It is also used to manage severe psoriasis and rheumatoid arthritis when other treatments have not been effective. Methotrexate works by slowing or stopping the growth of cancer cells and suppressing the immune system to reduce inflammation.

After taking methotrexate, it is recommended to flush the toilet twice to ensure that any residual medication in the urine is thoroughly removed. This precaution helps minimize the risk of exposure to others, as methotrexate can be harmful if it comes into contact with skin or is ingested.

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