Trexall

Drug Details

Methotrexate, also known by its brand name Trexall, is a versatile medication used in the treatment of certain cancers and non-cancerous conditions. As an antimetabolite, methotrexate is administered at high doses to target and destroy cancer cells, making it effective in treating cancers like acute lymphoblastic leukemia (ALL), non-Hodgkin's lymphoma, and cutaneous T-cell lymphoma. In lower doses, methotrexate acts as a disease-modifying antirheumatic drug (DMARD), which is beneficial in managing conditions such as rheumatoid arthritis (RA), polyarticular juvenile idiopathic arthritis (pJIA) in children, and severe psoriasis. This medication helps by slowing the growth of cancer cells and reducing the immune system's attack on healthy tissues. For most conditions, methotrexate is taken orally once a week, although some conditions may require a different dosing schedule. Common side effects include mouth sores, nausea, and stomach upset. Early intervention with methotrexate in rheumatoid arthritis can help prevent further joint damage and maintain joint function. Always consult a healthcare professional before starting any new treatment regimen.